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  • ZIB Catalog  (1)
  • Articles: DFG German National Licenses  (18)
  • 1995-1999  (19)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical psychology 6 (1999), S. 0 
    ISSN: 1468-2850
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: This literature review summarizes the psychometric properties of 12 measures used to assess readiness to change substance abuse. Assessment methods vary, and include algorithms, self-administered questionnaires, and clinical ratings. We describe each and summarize reliability and validity information. Some measures have poor psychometric properties, whereas limited psychometric data are available for others. No single measure emerges as best for use in clinical settings, and promising candidates differ regarding target population and assessment method. Although the Transtheoretical Model inspired much of the empirical work on readiness to change, the psychometric literature provides inconsistent support for the stages of change. Readiness to change may best be conceptualized as a multidimensional and continuous construct with complex relationships to behavior, cognition, and environmental context.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical psychology 3 (1996), S. 0 
    ISSN: 1468-2850
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: Seriously mentally ill adults are at high risk for human immunodeficiency virus (HIV) infection. We review the empirical literature that documents this elevated risk in psychiatric patients and identify factors that have been associated with enhanced risk. Our review indicates five characteristics related to HIV risk in psychiatric populations: psychopathology severity and symptomatology, substance abuse proximal to sexual behavior, misinformation about HIV transmission, perceptions of invulnerability, and sttuational, lifestyle factors. Understanding these characteristics can lead to improved HIV preventive intervention models. However, we also note that studies have been limited by unreliable psychiatric diagnoses and sampling constraints. We conclude with suggestions for research, practice, and prevention based on findings in the empirical literature and theories of HIV risk reduction.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Prostate cancer progresses from a hormone-sensitive, androgen-dependent stage to a hormone-refractory, androgen-independent tumor. The androgen receptor pathway functions in these androgen-independent tumors despite anti-androgen therapy. In our LAPC-4 prostate cancer model, androgen-independent ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 377 (1995), S. 254-257 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ZEBRA (also called Zta) is known to stimulate assembly of the DA complex in vitro1'5. We reasoned that if this was indeed a biologically relevant event then it should be included in the mechanism of transcriptional synergy6. The electrophoretic mobility shift assay in Fig. \a and the ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The VLDB journal 6 (1997), S. 241-256 
    ISSN: 0949-877X
    Keywords: Key words: Optimization – Cost models – Join methods – Buffer allocation – Performance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract. In this paper, we re-examine the results of prior work on methods for computing ad hoc joins. We develop a detailed cost model for predicting join algorithm performance, and we use the model to develop cost formulas for the major ad hoc join methods found in the relational database literature. We show that various pieces of “common wisdom” about join algorithm performance fail to hold up when analyzed carefully, and we use our detailed cost model to derive op timal buffer allocation schemes for each of the join methods examined here. We show that optimizing their buffer allocations can lead to large performance improvements, e.g., as much as a 400% improvement in some cases. We also validate our cost model's predictions by measuring an actual implementation of each join algorithm considered. The results of this work should be directly useful to implementors of relational query optimizers and query processing systems.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-3254
    Keywords: HIV ; AIDS ; knowledge ; measurement ; assessment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have developed and evaluated a self-administered questionnaire of knowledge about human immunodeficiency virus (HIV) infection for use in program evaluation. Formative work led to the development of the 62-item HIV-Knowledge Questionnaire (HIV-K-Q), which was administered to 409 women and 227 men. Item analyses resulted in the deletion of 17 items that were either too easy or did not correlate well with the total score. Factor analysis on the remaining 45 items resulted in a single factor labeled HIV Knowledge. The generalizability of this one-factor solution was confirmed with data from 285 women and 76 men. Reliability analyses revealed that the HIV-K-Q is internally consistent (alpha = .91) and stable over 1-week (r = .83), 2-week (r = .91), and 12-week (r = .90) intervals. Evidence for the validity of the HIV-K-Q was assembled using known groups and treatment outcome analyses. Additional evidence emerged from analyses that revealed associations between scores on the HIV-K-Q and two related knowledge measures, and between HIV-K-Q scores and level of educational attainment. Discriminant evidence was obtained through nonsignificant relationships between the HIV-K-Q and potentially biasing constructs, including social desirability. The HIV-K-Q requires a sixth-grade education, and 7 min to complete. The HIV-K-Q is a reliable, valid, and practical measure of HIV-related knowledge that can be used with low-literacy adults.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-3254
    Keywords: HIV ; AIDS ; women ; prevention ; qualitative methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Focus groups were conducted with 45 young, single, low-income women regarding the human immunodeficiency virus (HIV). Risk in this sample was substantial, as 53% had multiple sexual partners, and 55% reported a recent sexually transmitted disease. Qualitative analysis of transcribed focus groups identified six themes that emerged across groups: (a) misinformation about vertical transmission and treatment of HIV-related illnesses; (b) risk perception linked to emotive factors rather than objective data; (c) uncertainty regarding the risk-reducing value of monogamy; (d) fatalism linked with ambivalence about HIV-antibody testing and treatment; (e) recognition of the importance of discussing HIV-related topics with children, but concern that such discussion with other women might be inappropriate; and (f) inconsistent communication regarding HIV transmission and prevention with partners, partly the result of concerns about violating trust in intimate relationships. These themes warrant attention in the development of HIV risk-reduction programs.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Aids and behavior 3 (1999), S. 269-276 
    ISSN: 1573-3254
    Keywords: HIV ; prevention ; motivation ; skills ; behavior change
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This article advances the view that motivational strategies can augment the effectiveness of skills-based HIV risk reduction interventions. We articulate the empirical and theoretical rationale for a motivational approach and describe how we developed a motivationally based HIV risk reduction intervention. We also describe the strategic exercises and the therapeutic style that constitutes this approach, and then present detailed reviews of three clinical trials that have evaluated HIV-preventive motivational interventions. Results of these trials provide promising evidence for the integration of motivational approaches with traditional skills-based approaches. We recognize the limitations of existing research and provide suggestions for future investigations.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1439-6327
    Keywords: Key words Maximal intensity ; Phosphagens ; Type I and II muscle fibres ; Maximal oxygen consumption ; Enzyme activities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In contrast to endurance training, little research has been carried out to investigate the effects of short (〈10 s) sprint training on performance, muscle metabolism and fibre types. Nine fit male subjects performed a mean of 16 outdoor sprint running training sessions over 6 weeks. Distances sprinted were 30–80 m at 90–100% maximum speed and between 20 and 40 sprints were performed in each session. Endurance (maximal oxygen consumption; V˙O2 max), sprint (10 m and 40 m times), sustained sprint (supramaximal treadmill run) and repeated sprint (6 × 40 m sprints, 24 s recovery between each) performance tests were performed before and after training. Muscle biopsy samples (vastus lateralis) were also taken to examine changes in metabolites, enzyme activities and fibre types. After training, significant improvements were seen in 40 m time (P 〈 0.01), supramaximal treadmill run time (P 〈 0.05), repeated sprint performance (P 〈 0.05) and V˙O2 max (P 〈 0.01). Resting muscle concentrations of ATP and phosphocreatine did not change. Phosphorylase activity increased (P 〈 0.025), citrate synthase activity decreased (P 〈 0.01), but no significant changes were recorded in myokinase and phosphofructokinase activities. The proportion of type II muscle fibres increased significantly (P 〈 0.05). These results demonstrate that 6 weeks of short sprint training can improve endurance, sprint and repeated sprint ability in fit subjects. Increases in the proportion of type II muscle fibres are also possible with this type of training.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1439-6327
    Keywords: Key words High intensity exercise  ;  Muscle metabolism Oxygen deficit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This investigation determined the influence of pre-exercise muscle glycogen availability on performance during high intensity exercise. Nine trained male cyclists were studied during 75 s of all-out exercise on an air-braked cycle ergometer following muscle glycogen-lowering exercise and consumption of diets (energy content approximately 14 MJ) that were either high (HCHO – 80% CHO) or low (LCHO – 25% CHO) in carbohydrate content. The exercise-diet regimen was successful in producing differences in pre-exercise muscle glycogen contents [HCHO: 578(SEM 55) mmol · kg−1 dry mass; LCHO: 364 (SEM 58) P 〈 0.05 mmol · kg−1 dry mass]. Despite this difference in muscle glycogen availability, there were no between trial differences for peak power [HCHO 1185 (SEM 50)W, LCHO 1179 (SEM 48)W], mean power [HCHO 547 (SEM 5)W, LCHO 554 (SEM  8)W] and maximal accumulated oxygen deficit [HCHO 54.4 (SEM 2.3) ml · kg−1, LCHO 54.6 (SEM 2.0) ml · kg−1]. Postexercise muscle lactate contents (HCHO 95.9 (SEM 4.6) mmol · kg−1 dry mass, LCHO 82.7 (SEM 12.3) mmol · kg−1 dry mass, n = 8] were no different between the two trials, nor were venous blood lactate concentrations immediately after and during recovery from exercise. These results would indicate that increased muscle glycogen availability has no direct effect on performance during all-out high intensity exercise.
    Type of Medium: Electronic Resource
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