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  • Articles: DFG German National Licenses  (105)
  • Electronic Resource  (105)
  • 2000-2004  (7)
  • 1920-1924  (86)
  • 1850-1859  (2)
  • 1830-1839  (10)
  • Chemistry  (101)
  • Epidemiology  (2)
  • Keywords  (2)
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  • Articles: DFG German National Licenses  (105)
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  • Electronic Resource  (105)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 102 (1921), S. 287-294 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 53 (1920), S. 2034-2052 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1436-6274
    Keywords: Schlüsselwörter ; Mesenchymale Vorläuferzellen ; CFU-F ; Alkalische Phosphatase ; Klonales Wachstum ; Keywords ; Mesenchymal progenitor cells ; CFU-F ; Alkaline phosphatase ; Clonal growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: In 7 patients undergoing corrective surgery of the limbs, cancellous bone was harvested from the iliac crest. During this procedure bone marrow was aspirated. Mononuclear cells were isolated by density gradient centrifugation, and a clonal growth was initiated for CFU-F. Cultures were kept for 2, 3 and ¶4 weeks. In mean 5.6 × 105 mononuclear cells/ml aspirate were isolated. The average clonal efficiency was 4.5 colonies/ml aspirate. As a sign of osteogenic differentiation 15.3% (2 weeks), 42.2% (3 weeks) and 64.3% (4 weeks) of the areas of clonal growth stained positive for alkaline phosphatase. Immunostaining for osteocalcin showed a similar pattern confirming these results. These results suggest that human mesenchymal progenitors can be isolated from marrow punctures and that with matching culture conditions osteogenic differentiation is possible.
    Notes: Bei Spongiosaentnahmen im Rahmen aseptischer Eingriffe wurde bei 7 Patienten ein Knochenmarkaspirat vom vorderen Beckenkamm gewonnen. Die mononukleäre Zellfraktion wurde über Gradientenzentrifugationen isoliert, und die Zellen wurden in Form eines klonalen Wachstums gezüchtet. Die Kulturzeiten betrugen 2,3 und 4 Wochen. Im Mittel ließen sich 5,6 × 10 5 Zellen/ml Aspirat gewinnen. Die klonale Wachstumseffizienz betrug im Durchschnitt 4,5 Kolonien/ml Aspirat. Als Hinweis auf eine osteogene Differenzierung exprimierten nach ¶2 Wochen 15,3%, nach 3 Wochen 42,2% und nach 4 Wochen 64,3% Flächenanteil der Kolonien alkalische Phosphatase. Dieses Ergebnis konnte durch immunzytochemische Färbung auf Osteokalzin bestätigt werden. Die Ergebnisse zeigen, dass humane mesenchymale Vorläuferzellen aus dem Knochenmark isoliert und unter den passenden Kulturbedingungen in die osteogene Reihe differenziert werden können.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1436-6274
    Keywords: Schlüsselwörter ; Ventrale Spondylodese ; Funktionelles ¶Ergebnis ; Untere Halswirbelsäule ; Keywords ; Ventral spondylodesis ; Functional results ; Low cervical spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: A total of 58 patients were examined to determine the functional results in the cervical spine an average of 5.3 years after ventral spondylodesis. After questioning and physical examination the function was assessed by functional radiographs (according to Penning) and dynamic 3-D motion analysis. In 54% of cases the patients reported no subjective restrictions of their mobility or only slight restrictions, while 22% experienced moderate to marked limitations in their professional life and 28%, in their activities of daily living, but 84% of the patients were nonetheless still engaging in the same types of sport as before. The clinical examination revealed the following ranges of movement (MV ± SD) in the cervical spine: anteflexion 37°± 19°; retroflexion 46°± 21°; lateral bending 49°± 24°; and rotation in neutral position 112°± 42°. The functional radiographs showed smaller values: anteflexion 24.2°± 11°; and retroflexion 25.4°± 14°. The 3-D motion analysis confirmed a restriction compared with the normal collective: 20% in the sagittal plane, 13% in the frontal plane, 18% with rotation in the neutral position, 15% in maximal anteflexion and 26% in maximal retroflexion of the cervical spine. The function of the cervical spine is independent of age, sex and extent of the spinal fusion; restrictions tend to be more pronounced with increasingly caudally located spondylodeses. Compensatory hypermobility of the neighbouring segments cannot generally be confirmed.
    Notes: Durchschnittlich 5,3 Jahre nach ventraler Spondylodese wurden 58 Patienten hinsichtlich des funktionellen Ergebnisses der Halswirbelsäule nachuntersucht. Nach Befragung und klinischer Untersuchung wurde die Funktion mit Hilfe von Funktionsaufnahmen (nach Penning) und dynamischer 3D-Bewegungsanalyse beurteilt. Subjektiv keine oder geringe Einschränkungen der HWS-Beweglichkeit bemerkten 54% der Patienten, im Beruf sind 22% und im Alltag 28% mäßig bis stark eingeschränkt, dennoch üben 84% alte sportliche Aktivitäten aus. Die klinische Untersuchung ergab folgende Bewegungsauslenkungen (MW ± SD): Anteflexion: 37 ± 19°, Retroflexion: 46 ± 21°, bilaterale Seitneigung: 49 ± 24°, Rotation in Neutralstellung: 112 ± 42°. Die Funktionsaufnahmen zeigten geringere Werte: Anteflexion: 24,2 ± 11° und Retroflexion: 25,4 ± 14°. Die 3D-Bewegungsanalyse bestätigte eine Einschränkung gegenüber dem Normalkollektiv: in der Sagittalebene 20%, in der Frontalebene 13%, bei Rotation in der Neutralstellung 18%, in der maximalen Anteflexion 15% und in der maximalen Retroflexion 26%. Die Funktion der HWS war vom Alter, vom Geschlecht und von der Ausdehnung der Fusion unabhängig; kaudaler gelegene Spondylodesen zeigten tendenziell größere Einschränkungen. Kompensatorische Hypermobilitäten der benachbarten Segmente konnten im Regelfall nicht bestätigt werden.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Psychische Störungen ; Epidemiologie ; Erwachsene Allgemeinbevölkerung ; Prävalenz ; Standardisierte Diagnostik ; Key words Psychiatric disorders ; Epidemiology ; Adult general population ; Prevalence ; Standardized diagnostic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The present paper reports lifetime prevalence rates of mental disorders in the 18- to 64-year-old general population of a northern German region. A representative random sample from registration office files of 4,075 individuals was examined in personal interviews using the fully standardized and computerised “Munich Composite International Diagnostic Interview” (M-CIDI). The response rate was 70.2%. Individuals were classified according to the DSM-IV. Substance use disorders were most frequent with 25.8% followed by anxiety (15.1%), somatoform (12.9%), affective (12.3%), and eating disorders (0.7%). Disorders other than substance use were more frequent in women and less frequent in men. A trend toward less psychiatric morbidity exists in individuals with higher educational level, higher income, and those who are married or reside in rural communities. Of all individuals affected by mental disorders, 42% fulfilled the criteria for at least one additional disorder. The results are discussed against the background of selected previous studies.
    Notes: Zusammenfassung Im vorliegenden Beitrag werden Ergebnisse zur Lebenszeitprävalenz psychischer Störungen in der 18- bis 64-jährigen Allgemeinbevölkerung einer norddeutschen Region berichtet. 4.075 Personen einer zu 70,2% ausgeschöpften repräsentativen Einwohnermeldeamtsstichprobe wurden mit dem vollstandardisierten und computerisierten “Münchener Composite International Diagnostic Interview” (M-CIDI) in persönlichen Interviews untersucht. Die hier berichtete Klassifikation erfolgte auf Grundlage des DSM-IV. Störungen durch den Konsum psychotroper Substanzen stellten mit einer Lebenszeitprävalenz von 25,8% die häufigste Diagnosengruppe dar, gefolgt von Angststörungen (15,1%), somatoformen Störungen (12,9%), affektiven Störungen (12,3%) und Essstörungen (0,7%). Frauen waren dabei häufiger von nicht-substanzbezogenen psychischen Störungen betroffen und Männer häufiger von Substanzmissbrauch und -abhängigkeit. Es zeigt sich ein Trend zu geringerer psychiatrischer Morbidität bei Individuen mit höherer Schulbildung, höherem Einkommen, verheirateten Personen und Personen mit ländlichem Wohnsitz. 42% der Probanden mit einer Lebenszeitdiagnose erfüllten die Kriterien mindestens einer weiteren Störung. Die Ergebnisse werden im Kontext ausgewählter bisheriger Studien diskutiert.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1433-8491
    Keywords: Key words Obsessive-compulsive disorder ; Subclinical OCD ; Epidemiology ; Quality of life
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Despite the worldwide relevance of obsessive-compulsive disorder (OCD) there are considerable differences in prevalence rates and gender ratios between the studies and a substantial lack of prevalence data on subclinical OCD. Moreover, data on quality of life and on psychosocial function of subjects with OCD and subclinical OCD in the general population are missing to date. Methods: German versions of the DMS-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 4075 persons aged 18–64 years living in a northern Germany region. Specific DSM-IV based criteria for subclinical OCD were used. Results: The life-time prevalence rates for OCD and subclinical OCD were 0.5% and 2%, respectively. Twelve month prevalence rates were 0.39% and 1.6%, respectively. The gender female:male ratio was 5.7 in OCD and 1.2 in subclinical OCD. In various measures of psychosocial function and quality of life, OCD and subclinical OCD were significantly impaired. However, subclinical OCD subjects did not visit mental health professionals more often than controls. Conclusion: Due to different epidemiological characteristics subclinical OCD might represent a syndrome distinct from OCD which is also associated with significant impairments in personal and interpersonal functions and in quality of life.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 5 (1922), S. 315-344 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 5 (1922), S. 345-368 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 5 (1922), S. 581-593 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 5 (1922), S. 656-678 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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