ISSN:
1432-0584
Keywords:
Pesticides
;
Carbamates
;
DDT
;
Platelets
;
Prostaglandins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Aggregation of human platelets was investigated after pre-incubation of platelet rich plasma with various pesticides of the carbamate type. Whereas N-methyl-carbamates (insecticides) inhibited the arachidonic acid induced aggregation, N-phenyl-carbamates (herbicides) had no effect. The influence of the different carbamates on aggregation coincided with their inhibition of thromboxane B2-formation. — DDE, a metabolite of the insecticide DDT, affected aggregation to a similar extent as N-methyl-carbamates. DDT, however, had no inhibitory activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00320596
Permalink