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1

Digitale Medien

Colorimetric Determination of Sodium Lauryl Sulfate (1959)

Graham, H. D. ; Whitney, R. McL.

s.l. : American Chemical Society

Analytical chemistry 31 (1959), S. 1673-1676

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ISSN: 1520-6882

Quelle: ACS Legacy Archives

Thema: Chemie und Pharmazie

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1021/ac60154a038

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2

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General base catalysis, isotope effects, activation parameters, and the mechanism of removal of the hydrogen-bonded proton from protonated 1,8-bis(diethylamino)-2,7-dimethoxynaphthalene (1984)

Barnett, Graham H. ; Hibbert, Frank

s.l. : American Chemical Society

Journal of the American Chemical Society 106 (1984), S. 2080-2084

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ISSN: 1520-5126

Quelle: ACS Legacy Archives

Thema: Chemie und Pharmazie

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1021/ja00319a029

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3

Digitale Medien

Pascal in practice (1984)

Kirby, Graham H.

[s.l.] : Nature Publishing Group

Nature 309 (1984), S. 649-649

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] Pascal Applications for the Sciences: A Self-Teaching Guide. By Richard E. Crandall. Wiley: 1984. Pp.246. Pbk 13.90, 16.95. THE number of textbooks which deal with computer programming in Pascal is very large and still increasing. So it is refreshing to find that Richard CrandalPs book ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/309649b0

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4

Digitale Medien

FINANCIAL DECISIONS, THE COST(S) OF CAPITAL AND THE CAPITAL ASSET PRICING MODEL (1981)

Partington, Graham H.

Oxford, UK : Blackwell Publishing Ltd

Journal of business finance & accounting 8 (1981), S. 0

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ISSN: 1468-5957

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Wirtschaftswissenschaften

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1468-5957.1981.tb00806.x

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5

Digitale Medien

The delayed neuropathic effects of nerve agents and some other organophosphorus compounds (1983)

Gordon, James J. ; Inns, Robert H. ; Johnson, Martin K. ; [weitere]

Springer

Archives of toxicology 52 (1983), S. 71-82

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ISSN: 1432-0738

Schlagwort(e): Delayed neuropathy ; Neurotoxic esterase ; Nerve Agents: Sarin Soman Tabun VX ; bis[ω-phenyl-n-alkyl]phosphorofluoridates ; ω-phenyl-n-alkyl NN-dimethylphosphoramidofluoridate

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The in vitro inhibitory potencies of several nerve agents and other organophosphorus compounds against acetylcholinesterase (AChE) and neurotoxic esterase (NTE) have been compared. Although the I50s against AChE were about 0.1–1.0 nM for the nerve agents the I50s against NTE for sarin, soman and tabun were two to four orders of magnitude higher and VX had negligible activity. A series of bis[(ω-phenyl-n-alkyl]phosphorofluoridates inhibited both enzymes at 1.0–100 nM while ω-phenyl-n-alkyl NN-dimethylphosphoramidofluoridates were active at 0.1–10 μM. From the in vitro data it was predicted that nerve agents would cause delayed neuropathy only at doses greatly exceeding the LD50. In hens protected against acute toxicity by pretreatment with physostigmine, atropine and the oxime P2S, delayed neuropathy associated with high inhibition of NTE was found at 30–60 × LD50 for sarin but not at 38 × LD50 for soman or 82 × LD50 for tabun. At the maximum doses tested of the latter two compounds the inhibition of NTE was 55% and 66% respectively. The minimum neuropathic doses were calculated to be about 100–150 × LD50 for soman and tabun. As expected from in vitro data, neuropathy, associated with a high level of inhibition of NTE, was caused by one of the bis-phenylalkyl phosphorofluoridates at doses causing negligible acute toxicity. The required dose was 9X that for DFP although the compound was 300X more active against NTE in vitro suggesting that such compounds are rapidly degraded in vivo. The phenylalkyl NN-dimethylphosphoramidofluoridates produced prolonged acute signs of poisoning but they were not neuropathic at the maximum tolerable doses nor was the NTE greatly inhibited contrary to the prediction from the in vitro data. It is possible that the enantiomer responsible for the inhibition of NTE is preferentially degraded in vivo. Several other phosphoramidofluoridates inhibit NTE in vitro at 1.0–100 μM and a number of bicyclic phosphates were inactive at 23 μM. None of these compounds was tested in vivo.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00354767

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6

Digitale Medien

Equiconnectivity and cofibrations I (1981)

Heath, Philip R. ; Norton, Graham H.

Springer

Manuscripta mathematica 35 (1981), S. 53-68

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ISSN: 1432-1785

Quelle: Springer Online Journal Archives 1860-2000

Thema: Mathematik

Notizen: Abstract In this paper and its sequel, we generalize the notion of local equiconnectivity (LEC) given in [1] to that of h local equiconnectivity. We study these notions systematically using the theory of cofibrations and h cofibrations. Some classical results of locally equiconnected spaces are extended and generalized.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01168448

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7

Digitale Medien

Sterilization of oils: Data to support the use of a continuous point-of-use sterilizer (1984)

Bader, F. G. ; Boekeloo, M. K. ; Graham, H. E. ; [weitere]

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 26 (1984), S. 848-856

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ISSN: 0006-3592

Schlagwort(e): Chemistry ; Biochemistry and Biotechnology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: The continuous slow feed of animal and vegetable oils is frequently found to be an economically attractive method for maintaining antibiotic fermentations at a highly productive rate. The sterilization of oil feeds can present a major problem in the production plant. In this article, we present data and methodology on the kinetics of the thermal sterilization of No. 2 lard oil and soybean oil. It was also determined that dry heat sterilization condition could occur if dry spores were added to dry oil. This condition could only be partially alleviated by the addition of water to the oil. The theory and design of a small tubular coil continuous sterilizer for sterilizing oils at the point of use is also presented. This type of sterilizer is economical and versatile and simplifies control and instrument requirements. It provides a realistic alternative to the use of sterile feed tanks and sterile headers.

Zusätzliches Material: 11 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/bit.260260806

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