ISSN:
1434-4726
Keywords:
Inner ear pathology
;
Noise trauma
;
Electrophysiology
;
Electrocochleography
;
Diagnosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Low-frequency acoustic biasing using an intensive phase-shifted, low-frequency masker was studied according to its ability to determine disorders of cochlear micromechanics following noise trauma in the guinea pig as animal model. Statistical analyses proved that this technique allowed electrophysiological differentiation of controls versus groups with different degrees of experimentally induced threshold shifts. To substantiate group differences an intensity of at least 70 dB SPL was required for the 52 Hz masker and the difference in relation to the test-tone intensity had to be ±10 or ±20 dB SPL. The noise-traumatized cochlea could be identified by means of a threshold shift for the 5 μV pseudothreshold, a low modulation span of the compound action potential amplitude (〈 25–50μLV frequency dependent), and reduced positive summating potential amplitude with negative non-modulating values within the different measurement phases for 1 and 2kHz stimulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00171435
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