ISSN:
1433-3023
Keywords:
Estrogen replacement
;
Irritative voiding symptoms
;
Postmenopausal women
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Hormonal replacement therapy was carried out on 24 postmenopausal women who had chronic irritative lower urinary tract symptoms without definable causes. They all underwent bacteriological, endoscopic and urodynamic evaluations, and were diagnosed as having no abnormalities. Depot estradiol (4 mg i.m.) was administered for 2 months at 2-weekly intervals. Two patients discontinued the study because of genital bleeding. After the treatment subjective symptoms, including urinary frequency, urgency, urge incontinence, sense of incomplete emptying and lower abdominal discomfort, were relieved in more than 80% of the patients. Diurnal frequency and nocturia had significantly decreased. Urodynamic assessment revealed that volume at first sensation and maximum cystometric capacity were increased by estrogen therapy. It appeared that estrogen therapy improved the hypersensitivity of the lower urinary tract and relieved chronic voiding symptoms in postmenopausal women.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00460312
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