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  • Articles: DFG German National Licenses  (7)
  • 1975-1979  (7)
  • 1979  (7)
Source
  • Articles: DFG German National Licenses  (7)
Material
Years
  • 1975-1979  (7)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Lithium incorporation by vanadium pentoxide (1979)
    s.l. : American Chemical Society
    Inorganic chemistry 18 (1979), S. 2800-2803 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50200a034
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    THE EFFECTS OF CHRONIC REGIMENS OF CLORGYLINE AND PARGYLINE ON MONOAMINE METABOLISM IN THE RAT BRAIN (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 32 (1979), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of chronic administration of clorgyline and pargyline on rat brain monoamine metabolism have been examined. The inhibitory selectivity of these drugs towards serotonin deamina-tion (MAO type A) and phenylethylamine deamination (MAO type B) can be maintained over a 21-day period by proper selection of low doses of these drugs (0.5-1.0 mg/kg/24h). The results are consistent with MAO type A catalyzing the deamination of serotonin and norepinephrine and with MAO type B having little effect on these monoamines. Dopamine appears to be dcaminated in vivo principally by MAO type A. Clorgyline administration during a 3-week period was accompanied by persistent elevations in brain norepinephrine concentrations; serotonin levels were also increased during the first 2 weeks, but returned towards control levels by the third week of treatment. Low doses of pargyline did not increase brain monoamine concentrations, but treatment with higher doses for 3 weeks led to elevations in brain norepinephrine and 5-hydroxytryptamine; at this time significant MAO-A inhibition had developed. The changes in monoamine metabolism seen at the end of the chronic clorgyline regimen are not due to alterations in tryptophan hydroxylase activity. At this time tyrosine hydroxylase activity was also unaffected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1979.tb04508.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effects of clorgyline and pargyline on deaminated metabolites of norepinephrine, dopamine and serotonin in human cerebrospinal fluid (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 32 (1979), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1979.tb04533.x
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Male-pattern alopecia and masculinity (1979)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 100 (1979), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Cutaneous processes which are thought to be influenced by androgenic stimulation include the development of male-pattern alopecia, terminal hair distribution, sebum excretion rate, maximal sweat secretion rate and skin thickness. We measured these indices in forty-eight normal men, together with muscle, fat and bone thickness and plasma testosterone. There was a significant correlations between hair density on the forearm, leg and chest, but no other significant correlations were found. We conclude that bald men are no more ‘masculine’ than those with good scalp hair growth, if masculinity is defined in terms of end-organ response to androgenic stimulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1979.tb05582.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Cholinesterase in the atherosclerotic intima and in fibroblast cultures (1979)
    Springer
    Cellular and molecular life sciences 35 (1979), S. 377-378 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cholinesterase activity was present in the atheromatous plaque of the rabbit's atherosclerotic aorta. Cholinesterase activity was significantly increased in rat fibroblast cultures grown in the presence of hypercholesterolemic serum. Cholesterol ester synthesis in these cultures was inhibited by neostigmine, a cholinesterase inhibitor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01964363
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Brain region differences and some characteristics of monoamine oxidase type a and b activities in the vervet monkey (1979)
    Springer
    Neurochemical research 4 (1979), S. 53-62 
    Details
    ISSN: 1573-6903
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Monoamine oxidase in the vervet monkey showed greater variations in activity in six brain regions when tyramine or phenylethylamine was used as the substrate (3.8- to 4.1-fold differences) than when serotonin was the substrate (1.8-fold differences). With phenylethylamine and tyramine as substrates, the highest MAO specific activities were found in the hypothalamus and the lowest in the cerebellum and cortex. With serotonin as the substrate, the highest specific activities were in the mesencephalon and cortex. The inhibition of tyramine deamination by clorgyline and deprenyl yielded biphasic plots indicative of the presence of MAO-A and MAO-B enzyme forms in the vervet brain. On the basis of these inhibitor curves, the vervet brain could be estimated to contain approximately 85% MAO-B and 15% MAO-A, in contrast to rat brain which contains 45% MAO-B and 55% MAO-A. The inhibition of serotonin deamination by deprenyl in vervet brain yielded a biphasic plot, suggesting that some serotonin deamination in the vervet is accomplished by the MAO-B enzyme form. Estimations of the relative amounts of MAO-A and MAO-B based on inhibitor curves or based on substrate ratios yielded proportionate results which were in close agreement across the different brain regions, supporting the validity of these approaches to estimating MAO-A and MAO-B activities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00963831
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    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Practical considerations in the design of fast lowpass recursive digital filters for biomedical applications (1979)
    Springer
    Medical & biological engineering & computing 17 (1979), S. 383-386 
    Details
    ISSN: 1741-0444
    Keywords: Cutoff frequency ; E.C.G. ; Passband/stopband characteristics ; Recursive digital filters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A detailed investigation into the effect of altering the zero frequency f(0) and filter order M on the shape of the magnitude/frequency-response characteristics of lowpass, linear phase, integer multiplier, recursive digital filters is first carried Out. Using the results obtained from this investigation, a method, which may be used to design an Mth-order filter (M=1,2,3…) to a specified cutoff frequency f(3 dB), is derived. Then, the magnitude/frequency-response characteristics for 1st, 2nd and 3rd-order filters, having the same cutoff frequency, are compared and a procedure for optimising the filter characteristics for a specific application is suggested. Finally, the advantages of using this method for the digital filtering of the electrocardiogram are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02443827
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    Paper (German National Licenses)
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