ISSN:
1435-1536
Schlagwort(e):
5-fluorouracil
;
Sodium carboxymethylcellulose
;
Interaction
;
Enthalpy
;
Viscosity
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Maschinenbau
Notizen:
Abstract The interaction of an anticancer drug, 5-fluorouracil with sodium carboxymethylcellulose in aqueous solution was studied with a spectral method and viscosity measurement. From the binding data, the standard molar change in enthalpy, entropy and the number of binding sites on polymer were calculated. The standard molar change of enthalpy of 5-fluorouracil is about — 7 Kcal/mol with sodium carboxymethylcellulose. The enthalpy change is a considerably greater.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01452998
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