ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The translational energy, T, released during the loss of the angular 18- and 19-methyl groups both from metastable molecular ions and metastable [M — H2O]+ and [M — 2H2O]+ ions, in C(5)-unsaturated mono-and di-hydroxy steroids, as well as in their 19-nor and deuterated analogues bearing the label in the 19-methyl group, has been measured. It was found that, while the T values for the 19-CH3 loss, following the dehydration of the molecular ions, are increased substantially when compared to those for the same loss from the molecular ions, the T values for the 18-CH3 loss are increased much more moderately. Nevertheless, the amounts of translational energy released in the [M — H2O]+· — 18-CH3· and [M — 2 H2O]+· — 18-CH3· transitions are still higher than those found for the respective 19-methyl loss, in accordance with the general rule established recently.
Additional Material:
7 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210210306
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