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  • Articles: DFG German National Licenses  (2)
  • 2000-2004
  • 1990-1994  (2)
  • 1980-1984
  • 1990  (2)
  • 1
    ISSN: 1433-3023
    Keywords: Genuine stress urinary incontinence ; Maximum urethral closure pressure ; Pressure transmission ratio ; Recurrent stress urinary incontinence ; Urethral functional length
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this study 272 patients with genuine stress urinary incontinence (GSUI) were initially considered. Of these, 247 were divided into three groups based on: positive history for GSUI (group 1); positive history and clinical examination for GSUI (group 2); and positive history, clinical examination, and cough urethral pressure profile for GSUI (group 3). When compared with a group of 30 normal women (control group) the values for the urethral functional length (FL) and the maximum urethral closure pressure (MCUP) decreased progressively from group 1 to group 3. The pressure transmission ratio (PTR) was signficantly lower only in group 3. Tonometric values calculated for a group of 25 patients with GSUI recurring afterprevious surgical correction (group 4) were found to be comparable with group 3. These patients with recurrent GSUI had a FL decreased to 70% and a MCUP decreased to 48% of the normal values. The PTR was maintained at a normal value of 97% in patients with degree I recurrence, but was decreased to 68% in patients with degree II–III recurrence having the most severe impairment of the periurethral environment.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-6830
    Keywords: in situ hybridization ; nerve growth factor (NGF) ; NGF receptor (NGFR) ; cholinergic neurons
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. In situ hybridization histochemistry was used to localize nerve growth factor receptor (NGFR) mRNA in the adult rat basal forebrain. 2. In emulsion-dipped sections35S-labeled RNA antisense probes produced a high density of silver grains over cells located in the medial septum, vertical and horizontal limbs of the diagonal band of Broca, and nucleus basalis. 3. This distribution of NGFR mRNA overlaps with the distribution of NGFR protein localized using immunocytochemical techniques. 4. No hybridization signal was detected when sections were hybridized with a35S-labeled RNA sense (control) probe. 5. We suggest that NGFRs are synthesized in these basal forebrain nuclei and transported to terminal areas where NGF is thought to be bound and internalized, an initial step in the many actions of this neurotrophic factor.
    Type of Medium: Electronic Resource
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