ISSN:
1435-1536
Keywords:
Polymeremulsion
;
polymermicrosphhere
;
bovineserumalbumin
;
proteinadsurption
;
surfacehydrophilicity
;
surfaceheterogeneity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract The adsorption behaviors of bovine serum albumin (BSA) containing both dimeric and monomeric species onto polymer microspheres were examined using various homopolymers and poly(2-hydroxyethyl methacrylate)/polystyrene composite microspheres which were produced by the emulsifier-free (seeded) emulsion polymerization technique. The preferential adsorption of the BSA dimer was clearly observed in an optimum region of the surface hydrophilicities of the polymer microspheres. The preferential adsorption of the BSA dimer onto the composite polymer microspheres having heterogeneous surfaces consisting of hydrophilic and hydrophobic parts was more marked than those onto the homopolymer and copolymer microspheres having homogeneous surfaces.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01410399
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