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  • Articles: DFG German National Licenses  (4)
  • 1990-1994  (4)
  • 1991  (4)
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  • Articles: DFG German National Licenses  (4)
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  • 1990-1994  (4)
Year
  • 1
    facet.materialart.
    Unknown
    Boston, Mass., etc. : Periodicals Archive Online (PAO)
    The North American Review. 276:4 (1991:Dec.) 23 
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of regional science 31 (1991), S. 0 
    ISSN: 1467-9787
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geography , Economics
    Notes: . This paper presents a full-analogue regression model of the deterministic shift-share method, for analyzing the components of regional employment change. The model is formulated as a constrained least squares regression problem. This leads to a direct determination of estimates for the national, industrial, and regional growth coefficients. The statistical significance of these coefficients and the overall model can then be tested by using standard regression test statistics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0942-0940
    Keywords: Head injury ; outcome ; calcium antagonist ; nimodipine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We performed a randomised prospective double blind trial to study the effect of the calcium antagonist nimodipine on the outcome of head injured patients. The subjects were not obeying commands at the time of entry to the study, within 24 hours of injury. One hundred and seventy-five patients received nimodipine IV, 2 mg per hour for up to 7 days and 176 received placebo. The two groups were well matched for important prognostic features. Six months after injury 93 (53%) of the nimodipine group and 86 (49%) of the control group had a favourable outcome (moderate/good recovery). The relative increase in favourable outcomes (8%) was not significant but is compatible (95% C.I.) with an increase in favourable outcomes in treated patients by 33% or a decrease by 12%. Nimodipine was well tolerated and there were few adverse reactions; means of systolic and diastolic blood pressures and the intracranial pressure did not differ between the groups. It is unlikely that nimodipine has a marked effect on outcome (ie an increase in favourable outcome of 〉15%) after head injury of this severity but the study does not exclude a modest but clinically useful benefit.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 6 (1991), S. 179-183 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Cette étude examine le risque potentiel du lâchage anastomotique sur l'évolution à long terme des patients atteints d'un cancer colo-rectal. 167 malades ont été étudiés chez qui l'examen clinique et radiologique affirmait l'intégrité de l'anastomose dans la période postopératoire après une résection potentiellement curative pour cancer du colon gauche ou du rectum. Il n'y avait aucune évidence de lâchage anastomotique chez 135 de ces patients tandis que pour les 32 restants il existait une fuite clinique ou radiologique. A la fin d'un suivi moyen de 25 mois, 15 des malades avec fuite (46.9%) ont développé une récidive tumorale par comparaison avec 25 de ceux qui n'avaient aucune fuite (18.5%; p〈0.001). La mortalité spécifique par cancer à 24 mois était aussi significativement plus élevée pour les patients avec fuite anastomotique (36.9%±9.7% versus 12.6%±3.3%; p〈0.001). L'influence de la fuite anastomotique sur l'évolution était indépendante du stade de la tumeur. Ces résultats suggèrent que chez les patients qui subissent une résection chirurgicale pour cancer colo-rectal, l'apparition d'une fuite anastomotique est significativement associée avec une évolution à long terme plus péjorative.
    Notes: Abstract This study examines anastomotic leaks as a potential influence on the long term outcome of patients with colorectal cancer. 167 patients were studied who had clinical and radiological assessment of anastomotic integrity in the post-operative period, following potentially curative resections for left-sided colonic or rectal cancer. There was no evidence of a leak in 135 of these patients, while the remaining 32 developed a clinical and/or a radiological leak. At the end of a mean follow-up of 25 months, 15 patients with leaks (46.9%) developed tumour recurrence, compared with 25 of those without any leak (18.5%; p〈0.001). Cancer specific mortality at 24 months was also significantly higher for patients with leaks (36.9%±9.7% versus 12.6%±3.3%; p〈0.001). The influence of anastomotic leaks on the outcome was independent of tumour stage. These results suggest that in patients undergoing surgery for colorectal cancer development of an anastomotic leak is significantly associated with a poorer long-term outcome.
    Type of Medium: Electronic Resource
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