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  • Articles: DFG German National Licenses  (3)
  • 1990-1994  (3)
  • 1992  (3)
Source
  • Articles: DFG German National Licenses  (3)
Material
Years
  • 1990-1994  (3)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Sequence and functional analysis of the cloned Neisseria meningitidis CMP-NeuNAc synthetase (1992)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 96 (1992), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract The CMP-N-acetylneuraminic acid (CMP-NeuNAc) synthetase gene of Neisseria meningitidis group B is located on a 2.3-kb EcoRI fragment within the cps gene cluster. Nucleotide sequence determination of the gene encoding the CMP-NeuNAc synthetase revealed a 515-bp open reading frame that can encode a 18.9-kDA protein. A computer data base scan revealed a 59.4% identity to the CMP-NeuNAc synthetase gene of E. coli K1. Enzymatic activity was confirmed in vitro and in vivo. Transformation of the CMP-NeuNAc defective E. coli K1 strain EV5 with the meningococcal CMP-NeuNAc synthetase could complement the defect in E. coli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1992.tb05410.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Transformation-mediated exchange of virulence determinants by co-cultivation of pathogenic Neisseriae (1992)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 100 (1992), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract The horizontal flow of genetic material between microbes utilizes three principal routes: conjugation, transduction and transformation. While the significance in nature of the first two pathways is generally accepted, the in vivo role of transformation remains uncertain, despite the early observations by Griffith in 1928 on the transformation of streptococci from an avirulent to a virulent state [1]. Recently, circumstantial evidence was collected suggesting a role for transformation-mediated horizontal exchange in the modulation of virulence determinants of pathogenic Neisseriae and the variation of surface structures. In order to further assess the significance of transformation-mediated exchange we performed simple co-cultivation experiments of different Neisseria strains. We observed an efficient intra- and interspecies transfer of essential virulence determinants; the process was sensitive to the presence of DNaseI in the culture and was blocked in transformation-deficient recipients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1992.tb14062.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Measurements of the muon-neutrino mass (1992)
    Springer
    The European physical journal 56 (1992), S. S114 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The most precise upper limits for the muon-neutrino mass $$m_{v_\mu }$$ have been obtained by measuring the muon momentump μ + in pion decayπ +→μ+ v μ at rest. The current result for the squared neutrino mass, $$m_{v_\mu } ^2 = - 0.154 \pm 0.045MeV^2$$ , negative by 3.4 standard deviations, indicates that the experimental value for at least one of the three quantities used in the $$\left( {m_{v_\mu } ^2 } \right) -$$ derivation (p μ +,m π+,m μ+) is wrong.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02426784
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    Paper (German National Licenses)
    Fulltext
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