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  • Articles: DFG German National Licenses  (3)
  • 1995-1999  (3)
  • 1965-1969
  • 1999  (3)
  • ILLNESS  (2)
  • Dopamine
  • General Chemistry
  • Life and Medical Sciences
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  • Articles: DFG German National Licenses  (3)
Material
Years
  • 1995-1999  (3)
  • 1965-1969
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Effects of dopamine and serotonin-releasing agents on methamphetamine discrimination and self-administration in rats (1999)
    Springer
    Psychopharmacology 141 (1999), S. 287-296 
    Details
    ISSN: 1432-2072
    Keywords: Key words Methamphetamine ; Dopamine ; Serotonin ; Phentermine ; Fenfluramine ; Drug-discrimination ; Self-administration ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  To analyze the involvement of dopamine (DA) and serotonin (5-HT) release in the stimulus properties of methamphetamine, two amphetamine analogs that selectively release either brain DA (phentermine) or 5-HT (fenfluramine) were tested for their ability to substitute for methamphetamine in rats discriminating methamphetamine (1.0 mg/kg) from saline. They were subsequently tested for their ability to alter IV methamphetamine (0.06 mg/kg per injection) self-administration in the same species when given as a pretreatment. The DA releaser phentermine, like methamphetamine itself, decreased methamphetamine self-administration (to 70% of baseline responding), but only at a dose of 3.0 mg/kg that fully generalized to the methamphetamine stimulus in the discrimination study. The 5-HT releaser fenfluramine attenuated methamphetamine self-administration to a much larger extent than phentermine (to 37% of baseline responding) at a dose of 1.8 mg/kg that did not generalize to methamphetamine and did not decrease rate of responding in the discrimination study. Tolerance developed to the inhibitory effect of 1.8 mg/kg fenfluramine on methamphetamine self-administration when it was given repeatedly over four consecutive daily sessions. The fenfluramine-induced decrease in methamphetamine self-administration was also attenuated when it was given together with the small 1.0 mg/kg dose of phentermine. These results suggest that DA release plays a dominant role in the discriminative stimulus effects of methamphetamine. However, stimulation of 5-HT release can strongly modify methamphetamine self-administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050836
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Does God Determine Your Health? The God Locus of Health Control Scale (1999)
    Springer
    Cognitive therapy and research 23 (1999), S. 131-142 
    Details
    ISSN: 1573-2819
    Keywords: CONTROL ; RELIGION ; HEALTH ; ILLNESS ; MEASUREMENT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract Although perceptions of internal control havebeen related to physical and psychosocial outcomes inchronic illness,less attention has been paid toperceptions of external sources of control and theirimplications for adaptation. One reason for this has beenthe dearth of adequate measures for assessing specificexternal control constructs. The God Locus of HealthControl (GLHC) scale was developed to assess the extent of an individual's belief that God controls hisor her health status. The GLHC was designed as anadjunct to the widely used Multidimensional Health Locusof Control (MHLC) scales. Initial studies of the psychometric properties of the GLHC scale insamples of persons with two rheumatic diseases,rheumatoid arthritis and systemic sclerosis, provideevidence of the scale's reliability andvalidity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018723010685
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Appearance Self-Esteem in Systemic Sclerosis (1999)
    Springer
    Cognitive therapy and research 23 (1999), S. 197-208 
    Details
    ISSN: 1573-2819
    Keywords: APPEARANCE ; BODY IMAGE ; SELF-ESTEEM ; ILLNESS ; SCLERODERMA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract Although disease- and/or treatment-relatedchanges in physical appearance accompany many illnesses,the relationship of these physical changes to appearanceselfesteem and overall psychological adjustment has received little attention in the literature. Inthis study, subjects were 93 persons with diagnoses ofsystemic sclerosis, a chronic and progressive rheumaticdisease characterized by physical changes, especially skin thickening. Subjects receivedclinical examinations of skin thickening and providedself-reports via questionnaires of theirappearance-related self-esteem and overall psychologicaldistress. Results showed that disease-related physicalchanges were related to appearance self-esteem. Stepwisemultiple regression analysis found skin thickening ofthe righthand and fingers to be the strongest predictors of appearance self-esteem. Appearanceself-esteem was examined as a possible moderator ormediator of the relationship between skin thickening andpsychological distress. Results did not support amoderator role for appearance self-esteem; however,appearance self-esteem met statistical criteria as amediator of the relationship between skin thickening anddistress. Interestingly, results differed for thediffuse and limited subtypes ofsystemicsclerosis,suggesting that physical changes associatedwith disease may have stronger relationships withself-esteem and overall adjustment in the context ofless serious illnesses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018783329341
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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