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  • 1
    Electronic Resource
    Electronic Resource
    OEEPE/ISPRS JOINT WORKSHOP ON SPATIAL DATA QUALITY MANAGEMENT (2002)
    Oxford, UK : Blackwell Publishing Ltd
    The @photogrammetric record 17 (2002), S. 0 
    Details
    ISSN: 1477-9730
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1477-9730.2002.tb01910.x
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  • 2
    Electronic Resource
    Electronic Resource
    Hydrophobic Protein that Copurifies with Human Brain Acetylcholinesterase (2000)
    Oxford UK : Blackwell Science Ltd.
    Journal of neurochemistry 74 (2000), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The mechanism of attachment of acetylcholinesterase (AChE) to neuronal membranes in interneuronal synapses is poorly understood. We have isolated, sequenced, and cloned a hydrophobic protein that copurifies with AChE from human caudate nucleus and that we propose forms a part of a complex of membrane proteins attached to this enzyme. It is a short protein of 136 amino acids and has a molecular mass of 18 kDa. The sequence contains stretches of both hydrophobic and hydrophilic amino acids and two cysteine residues. Analysis of the genomic sequence reveals that the coding region is divided among five short exons. Fluorescence in situ hybridization localizes the gene to chromosome 6p21.32-p21.2. Northern blot analysis shows that this gene is widely expressed in the brain with an expression pattern that parallels that of AChE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2000.0742146.x
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  • 3
    Electronic Resource
    Electronic Resource
    Observation of a magic discrete family of ultrabright Si nanoparticles (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 841-843 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We demonstrate that electrochemically etched, hydrogen capped SinHx clusters with n larger than 20 are obtained within a family of discrete sizes. These sizes are 1.0 (Si29), 1.67 (Si123), 2.15, 2.9, and 3.7 nm in diameter. We characterize the particles via direct electron imaging, excitation and emission optical spectroscopy, and colloidal crystallization. The band gaps and emission bands are measured. The smallest four are ultrabright blue, green, yellow and red luminescent particles. The availability of discrete sizes and distinct emission in the red, green and blue (RGB) range is useful for biomedical tagging, RGB displays, and flash memories. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1435802
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  • 4
    Electronic Resource
    Electronic Resource
    Observation of laser oscillation in aggregates of ultrasmall silicon nanoparticles (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 121-123 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report laser oscillation at ∼610 nm in aggregates of ultrasmall elemental Si nanoparticles. The particles are ultrabright red emitting, dispersed from bulk Si by electrochemistry. The aggregates are excited by radiation at 550–570 nm from a mercury lamp. Intense directed Gaussian beams, with a threshold, manifest the emission. We observe line narrowing, and speckle patterns, indicating spatial coherence. This microlasing constitutes an important step towards the realization of a laser on a chip, hence optoelectronics integration and optical interconnects. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1428622
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  • 5
    Electronic Resource
    Electronic Resource
    A reply (2002)
    Oxford, UK : Blackwell Science, Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.2470_9.x
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  • 6
    Electronic Resource
    Electronic Resource
    The influence of sample dimensions on hydroxyl ion release from calcium hydroxide products (2000)
    Copenhagen : Munksgaard International Publishers
    Dental traumatology 16 (2000), S. 0 
    Details
    ISSN: 1600-0595
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract – The purpose of this study was to compare the rate of hydroxyl ion release from commercially available setting and non-setting calcium hydroxide products. The rate of hydroxyl ion release is important, as this has been suggested to be the main factor in the therapeutic activity of these products. In total, hydroxyl ion release was measured from 1104 samples of Dycal, Life, Calasept and Hypocal in solution using in vitro titration. The rate of hydroxyl ion release was measured for up to 14 days, using two sizes of sample surface area. The dimensions of the exposed sample surface area was found to be an important physical constraint to the hydroxyl ion release from non-setting calcium hydroxide products, whereas this was not found to be the case with setting products. The range in hydroxide activity between products was found to be 298%. In rank order of hydroxide ion release, from the most to the least active was: Hypocal, Calasept, Life and Dycal. The differences in the rate of hydroxyl ion release from these products may have some implications for their clinical applications. It is suggested that in cases where the oral healing responses have been poorer than expected, the size and seal of prepared cavities could have negatively influenced the therapeutic release of hydroxyl ions from non-setting calcium hydroxide products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-9657.2000.016006251.x
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  • 7
    Electronic Resource
    Electronic Resource
    Grass cells ingested by ruminants undergo autolysis which differs from senescence: implications for grass breeding targets and livestock production (2002)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 25 (2002), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: It is widely believed that the initial degradation of proteins contained in grazed forage is mediated by rumen micro-organisms, but the authors’ recent work suggests that the plant cells themselves contribute to their own demise. In the present study the responses of Lolium perenne leaves to the rumen environment were investigated by using an in vitro system which simulates the main stresses of the rumen but from which rumen micro-organisms were excluded. Degradation of leaf protein and the accumulation of amino acids in tissue and bathing medium occurred over a time-scale that is relevant to rumen function, and in a near 1 : 1 ratio. Significant loss of nuclear material was observed after 6 h incubation and chloroplasts became morphologically more spherical as the incubation progressed. In situ localization suggested that ribulose 1,5 bisphosphate carboxylase/oxygenase was broken down within chloroplasts which from cytology were judged to be intact. We conclude from these data that plant metabolism may play a significant role in breaking down plant proteins within relatively intact organelles in the rumen. The determinations of chlorophyll content and cell viability revealed that the plant processes occurring in the simulated rumen were similar but not identical to those of natural senescence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2002.00908.x
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  • 8
    Electronic Resource
    Electronic Resource
    Multiple basal cell carcinomas and malignant melanoma following radiotherapy for ankylosing spondylitis (2000)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 25 (2000), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We present the case of a 53-year-old Caucasian woman with seven basal cell carcinomas and one malignant melanoma in situ along her back overlying her spine, which was irradiated in 1968 for ankylosing spondylitis. These lesions developed between 1997 and 1999. She has no other known risk factors for cutaneous malignancy, in particular no history of excessive sun exposure. She has skin type 2. Molecular studies of glutathione S-transferase and cytochrome P450 status showed her genotype not to constitute an overall increased inherited susceptibility. We therefore postulate that all her skin cancers have arisen as a consequence of her radiotherapy. To our knowledge this is the first case of multiple basal cell carcinoma in addition to a malignant melanoma following radiotherapy for benign disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2000.00668.x
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  • 9
    Electronic Resource
    Electronic Resource
    Midazolam – an anti-emetic? (2002)
    Oxford, UK : Blackwell Science, Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.2575_19.x
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  • 10
    Electronic Resource
    Electronic Resource
    Use of a chimeric ELISA to investigate immunoglobulin E antibody responses to Der p 1 and Der p 2 in mite-allergic patients with asthma, wheezing and/or rhinitis (2002)
    Oxford, UK : Blackwell Science, Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Sensitization to indoor allergens, particularly to dust mites, is a strong risk factor for asthma in children and adults. Assessment of sensitization is carried out using in vivo and in vitro tests to detect specific IgE antibodies.Objective To investigate IgE antibody responses to mites in patients with asthma, wheezing and/or rhinitis, using chimeric ELISA to measure specific IgE antibodies to mite allergens Der p 1 and Der p 2.Methods Specific IgE antibodies to Der p 1 and Der p 2 were quantified by chimeric ELISA, and compared with IgE to Dermatophagoides pteronyssinus (Dpt) measured using the CAP system (Pharmacia). A panel of sera from 212 patients with asthma, wheezing and/or rhinitis and 11 controls was analysed.Results There was a significant correlation between IgE to Dpt measured by CAP and IgE to Der p 1 (r = 0.81, P 〈 0.001), Der p 2 (r = 0.79, P 〈 0.001) and combined Der p 1 and Der p 2 (r = 0.86, P 〈 0.001). Seventy per cent of all patients had IgE to Dpt, and of those, 76.5% had IgE to Der p 1, 79.2% had IgE to Der p 2 and 83.1% had IgE to Der p 1 and Der p 2 combined. Considering the cut-off level of 2 IU/mL of IgE to either Der p 1 or Der p 2, the predictive value for a positive IgE to Dpt by CAP was greater than 95%.Conclusions The chimeric ELISA allowed accurate quantification of IgE antibodies to Dpt allergens Der p 1 and Der p 2, and it could be useful for studying immune responses to mites in patients with asthma and/or rhinitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2745.2002.01455.x
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