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  • Articles: DFG German National Licenses  (5)
  • 2005-2009  (1)
  • 1975-1979  (4)
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  • Articles: DFG German National Licenses  (5)
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Year
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  • 1
    Electronic Resource
    Electronic Resource
    Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitors in vitro (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Dendritic arbor development of subventricular zone-derived interneurons is a critical step in their integration into functional circuits of the postnatal olfactory bulb. However, the mechanism and molecular control of this process remain unknown. In this study, we have developed a culture model where dendritic development of purified subventricular zone cells proceeds under serum-free conditions in the absence of added growth factors and non-neural cells. We demonstrate that the large majority of these cells in culture express GABA and elaborate dendritic arbors with spine-like protrusions but they do not possess axons. These neurons expressed receptors for neurotrophins including p75, TrkB and TrkC but not TrkA. Application of exogenous neurotrophins, including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and nerve growth factor (NGF), to cultures stimulated dendritic growth and led to more complex dendritic arbors during the initial 3 days in culture. Our results suggest that these effects are independent of Trk receptors and mediated by the p75/ceramide signaling pathway. We also show that brain-derived neurotrophic factor is the only neurotrophin that is able to influence late-phase dendritic development via TrkB receptor activation. These results suggest that dendritic arbor development of subventricular zone-derived cells may be regulated by neurotrophins through the activation of p75 and the TrkB receptor signaling pathways in a sequentially defined temporal pattern.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03849.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Electrical potentials in epithelial neoplasms (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 96 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb07166.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    p-Bis-(trimethylsilyl)benzene (1975)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 31 (1975), S. 1787-1789 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S056774087500619X
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Octamethylbicyclopentasiloxane (1975)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 31 (1975), S. 1214-1217 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567740875004876
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Autoradiographic studies on the protein synthesis and the distribution of the newly synthesized proteins in oligodendroglial cells (1975)
    Springer
    Cell & tissue research 159 (1975), S. 267-277 
    Details
    ISSN: 1432-0878
    Keywords: Hippocampus ; Oligodendroglial cells ; Protein synthesis ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The protein-synthesizing activity of oligodendroglial cells in the rat hippocampus as well as the migration of the newly synthesized proteins within these cells were examined by means of light and electron microscopic autoradiography when injecting 3H-leucine into the lateral ventricle. The autoradiographs of oligodendroglial cells were compared with the autoradiographs of hippocampal pyramidal cells of the same area. According to the quantitative evaluation of the autoradiographs the protein-synthesizing activity of the oligodendrocytes equals or may even exceed that of the pyramidal cells. In oligodendroglial cells most of the newly synthesized proteins migrate very rapidly from the rough-surfaced endoplasmic reticulum into the cisternae of the Golgi apparatus and disappear continuously. The proteins disappear from the Golgi apparatus simultaneously with the decrease in the radioactive concentration of the perikaryon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219161
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    Paper (German National Licenses)
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