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  • Articles: DFG German National Licenses  (2)
  • 2005-2009  (2)
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  • Articles: DFG German National Licenses  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing
    Psychophysiology 42 (2005), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Startle eyeblink modification was measured during a continuous performance test (CPT) with either clearly focused stimuli or visually degraded stimuli to measure the effects of early perceptual processing demands on startle modification. A startling noise was presented either 120, 240, or 1200 ms following target and nontarget CPT stimuli. In the degraded stimulus CPT, startle inhibition at 240 ms was greater following targets than nontargets and was as great during targets at 240 ms as at 120 ms, whereas in the clearly focused CPT, inhibition declined significantly from 120 to 240 ms. The results indicate that maximum prepulse inhibition is extended in time when the task involves discrimination of degraded visual stimuli and when early perceptual processing demands are high. At 1200 ms, targets and nontargets produced nondifferential inhibition during both CPTs, suggesting that modality-specific attention occurred equally for the two tasks.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The ability of electrodermal variables to predict negative symptoms and functional outcome over a 1-year period in schizophrenia was investigated in 78 young, recent-onset outpatients. Patients were stabilized on standardized medication and largely free of psychotic symptoms. Higher levels of both tonic (skin conductance level, nonspecific skin conductance response rate) and phasic (number of skin conductance orienting responses) activity were associated with more negative symptoms and with a combination of poorer social and occupational outcome at 1-year follow-up. This pattern was seen in both male and female patients, and in older and younger patients. Results are interpreted as suggesting that high levels of arousal and overreactivity to the environment may interfere with efficient cognitive processing in schizophrenia, contributing to poor outcome, and that negative symptoms might partially serve as a means of coping with overarousal.
    Type of Medium: Electronic Resource
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