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  • Articles: DFG German National Licenses  (5)
  • 2000-2004  (3)
  • 1970-1974  (2)
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  • Articles: DFG German National Licenses  (5)
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Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Tumor inhibitors. LXXIII. Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus (1972)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 94 (1972), S. 1354-1356 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00759a054
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The culture of benthic marine algae in the laboratory and the field (1970)
    Springer
    Helgoland marine research 20 (1970), S. 62-69 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary 1. Growth and development of algae from spores has been observed in the laboratory (Menai Bridge) and under field conditions at Ravenspoint (West coast of Anglesey). Attempts were made to culture all main components of the sub-littoral flora. Spore material was obtained from spores allowed to settle onto plastic slides in the laboratory sea water system and from spores settled on slides stationed in the field. 2. Attention was given to the summer annual species and, in particular, to those members of the Nemalionales (Rhodophyceae) which have incompletely known life histories. In these plants, the tetrasporic phase during which reduction division normally takes place, has so far been undetected in the field. The plants are represented by the cystocarpic phase of the life cycle only. 3. The fate of the carpospores of these species were of particular interest. The spores of the annual species were cultivated under a number of regimes of irradiation and temperature. Sporelings from laboratory culture were transferred to the field in November, 2 months after settlement. Both in laboratory and field, the form of development of the cultures were similar until May of the following year. Then the field cultures developed structures which may represent the tetrasporangia of the alternate phase. These structures failed to develop in the laboratory cultures after 3 years. 4. The results of these experiments illustrate that care must be taken in interpreting results of laboratory cultures of algae, in particular in regard to their life histories.
    Notes: Kurzfassung Der Aspekt der sublitoralen Algenvegetation vor der Küste von Ravenspoint (Westküste von Anglesey) wird entscheidend von der mechanischen Wellenwirkung, der Trübung des Wassers und der Sedimentierung geprägt. Auf den durch die Winterstürme stark verlagerten und abgescheuerten Steinen in 4 m Tiefe dicht unter der Küste kann sich erst ab April-Mai eine üppige Vegetation annueller Arten entwickeln. In 9 m Tiefe überstehen nur derbere Formen wieChondrus oderFurcellaria die winterliche Sedimentablagerung. Hier stellen sich in den Somermonaten außer den auch in 4 m vorkommenden Arten einjährige Rotalgen wieNaccaria, Halarachnion, Scinaia undHelminthora ein. Zur Klärung ihrer Ökologie und Lebensgeschichte wurden Steine ins Laboratorium verbracht und der sich entwickelnde Aufwuchs untersucht, außerdem Kulturen dieser Arten auf Objektträgern im Laboratorium und am natürlichen Standort verglichen. Besonderes Interesse verdienen Vertreter der Nemalionales (Rhodophyceae), in deren Lebenszyklus bisher nur die karposporentragende Phase bekannt ist. Zwei Monate alte Kulturen vonNaccaria wurden im November aus dem Laboratorium an ihren natürlichen Standort gebracht. Nach gleichartiger Entwicklung bis zum Mai des folgenden Jahres bildeten sie Strukturen, die vielleicht der tetrasporentragenden Phase entsprechen. Solche Stadien wurden während der dreijährigen Kultur im Laboratorium nicht beobachtet. Daher ist eine kritische Beurteilung der an Laboratoriumskulturen erhaltenen Ergebnisse angezeigt, besonders bei der Untersuchung des Lebenszyklus von Algen. Die Zellenanordnung junger Corallinaceen-Krusten zeigte charakteristische Unterschiede, die vielleicht als taxonomische Kriterien verwertbar sind.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01609887
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immediate IL-10 expression following major orthopaedic trauma: relationship to anti-inflammatory response and subsequent development of sepsis (2000)
    Springer
    Intensive care medicine 26 (2000), S. 1076-1081 
    Details
    ISSN: 1432-1238
    Keywords: Key words IL-10 ; HLA-DR ; Inflammation ; Sepsis ; Intensive care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To assess the relationship between IL-10 release and anti-inflammatory response following blunt trauma. Design: Prospective longitudinal clinical study. Setting: Departments of trauma and anaesthetics in a university teaching hospital Patients: Forty-eight adult patients with a mean injury severity score of 14.5 (range 9–57) were prospectively studied following blunt trauma. Measurements and results: Venous blood samples were collected on arrival and at 16 and 24 h, and at 3, 5, and 7 days. Peripheral blood mononuclear cell (HLA-DR) expression on CD14 + monocytes was quantified by flow cytometry and serum IL-10 was assayed by ELISA. Anti-inflammatory response was defined as monocyte HLA-DR expression of less than 30 % of that seen in healthy controls. Serum IL-10 levels in trauma patients on arrival was significantly elevated, 70.0 [48.0–92.1, 95 % confidence interval, (CI)] compared to the control group, 3 (0–5) (P 〈 0.0001), and monocyte HLA-DR expression was significantly lower, 14.2 (12.1–16.3, 95 % CI), in patients versus 25.2 (22.4–28.1) in controls (P 〈 0.001). Patients with low HLA-DR expression (n = 14) had significantly higher serum IL-10 levels than those whose HLA-DR expression remained above 30 % of the control value (n = 34), (P 〈 0.038). In patients who developed sepsis (n = 11), serum IL-10 levels were greater on admission, [143.7 (80.2–207.2) pg/ml–1], and remained elevated during the study period compared with non-complicated patients, [50.16 (33.5–66.8) pg/ml–1]. Immediate IL-10 (2 h following trauma) was negatively correlated with simultaneous HLA-DR expression, (r = –0.49, P = 0.0005). Conclusion: These findings support the view that IL-10 release regulates monocyte HLA-DR expression and may be related to an anti-inflammatory response and development of sepsis following trauma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051320
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Compartment syndrome following isolated ankle fracture (2000)
    Springer
    International orthopaedics 24 (2000), S. 173-175 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé   Nous rapportons deux cas de syndrome de loge qui suit des fractures de la cheville isolées. Les 2 cos ont nécessité une décompression de tous les compartiments aprés un diagnostic précoce et la prise des pressions intra-compartimentales.
    Notes: Abstract  We report two cases of compartment syndrome following isolated ankle fractures. Both required decompression of all the compartments following early clinical diagnosis and measurements of the intra-compartmental pressures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002640000128
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Simultaneous bilateral femoral fractures: systemic complications in 14 cases (2000)
    Springer
    International orthopaedics 24 (2000), S. 264-267 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé  Nous avons examiné rétrospectivement 14 patients avec une fracture fémorale bilatérale traités dans notre institution entre janvier 1993 et mars 1999. L"age moyen était de 38 ans (19–75) et le score moyen de la sevérité de la blessure (ISS) 16 ( 10–20). 13 malades ont été traités par enclouage centro médullaire et un avec plaque et clou dans les 24 heures suivant l"admission. Les exigences moyennes de la réanimation étaient de 10.6 (6–16) litres de colloîde et cristalloide et 8.6 (4–30) unités de sang. Le ratio séjour en soins intensifs/séjour en soins hautement intensifs était de 4 (1–14) et la durée moyenne de séjour à l"hôpital était 36.3 jours (3–210). Il y avait 6 cas de syndrome de détresse respiratoire adulte (ARDS), 1 syndrome de loge, 1 cas d"osteomyelite, 1 amputation au-dessus du genou et 2 morts (14.2%). La comparaison avec des patients atteints de façon unilatérale a révélé un plus haut degré de score ISS, d"exigences de la réanimation, de détresse respiratoire, de séjour de l"hôpital et de mortalité.
    Notes: Abstract  We have retrospectively reviewed 14 patients with bilateral femoral shaft fractures who attended our institution between January 1993 and March 1999. The mean age of the patients was 38 years (19–75) and the median injury severity score (ISS) was 16 (interquartile range 10–20). Thirteen patients were treated with intramedullary nailing and 1 with plating and nailing within 24 h of admission to hospital. The mean resuscitation requirements were 10.6 (6–16) litres of colloid and crystalloid and 8.6 (4–30) units of blood. The mean intensive care unit/high dependency unit (ICU/HDU) stay was 4 days (1–14) and the mean hospital stay was 36.3 days (3–210). There were 6 cases of adult respiratory distress syndrome (ARDS), 1 compartment syndrome, 1 case of osteomyelitis, 1 above-knee amputation and 2 deaths (14.2%). The mean time to union was 24.5 weeks (12–37). Comparison to patients with unilateral injuries revealed a higher ISS, resuscitation requirements, ARDS, hospital stay and mortality.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002640000161
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    Paper (German National Licenses)
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