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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 88 (2000), S. 2166-2168 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We show that small in-plane magnetization components in magnetic garnet films with perpendicular anisotropy can be imaged using nonlinear magneto-optical proximal probe microscopy, i.e., magnetization-induced second harmonic generation together with a scanning near-field optical microscope. A relationship exists between the in-plane magnetization domains we observed and the typical maze-like out-of-plane magnetization domains that are simultaneously imaged recording the linear Faraday effect. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  The literature has documented a controversial discussion on the possible relationship of otogenous symptoms and craniomandibular dysfunction since the 1920s. Therefore, an investigation was conducted which consisted of two parts: a case study with population-based controls and a cross-sectional study. The aim of the first study was to screen a group of patients suffering from acute or chronic tinnitus for temporomandibular disorders (TMD) in comparison with a population-based group of volunteers without tinnitus. To this end, 30 patients (13 females and 17 males, age 18–71 years) suffering from acute hearing loss associated with tinnitus, isolated acute tinnitus, and chronically transient tinnitus were examined for symptoms of craniomandibular dysfunction. The results were compared with those of clinical functional analysis from 1907 subjects selected representatively and according to age distribution from the epidemiological ‘Study of Health in Pomerania’ (SHIP); the occurrence of tinnitus was ruled out in these control subjects. Statistical analysis was performed with Chi-square and Mann–Whitney U-tests. Sixty per cent of the tinnitus patients and 36·5% of the control subjects exhibited more than two symptoms of TMD (P = 0·004). Tinnitus patients had significantly more muscle palpation pain (P 〈 0·001), temporomandibular joint (TMJ) palpation pain (P 〈 0·001), and pain upon mouth opening (P 〈 0·001) than the general population group. No statistical differences were found in TMJ sounds, limitation of mandibular movement, or hypermobility of the TMJ. Furthermore, 4228 subjects of the population group examined in the epidemiological study were screened for co-factors of tinnitus with the help of a multivariate logistic regression model which was adjusted for gender, age, and a variety of anamnestic and examined data. Increased odds ratios (OR) were found for tenderness of the masticatory muscles (OR = 1·6 for one to three painful muscles and OR = 2·53 for four or more painful muscles), TMJ tenderness to dorsal cranial compression (OR = 2·99), listlessness (OR = 2·0) and frequent headache (OR = 1·84) A relationship between tinnitus and TMD was established in both examinations. Tinnitus patients seem to suffer especially from myofascial and TMJ pain. A screening for TMD should be included in the diagnostic survey for tinnitus patients.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Reelin is an extracellular matrix protein secreted by a variety of cell types throughout the developing brain. The target cells for reelin express the cytoplasmic adapter protein Dab1, which binds to the reelin receptors VLDLR and ApoER2. In the present work, we have studied the localization of both receptors in developing mouse and human cortex, olfactory bulb and cerebellum. In mouse, some Cajal–Retzius cells express reelin and VLDLR; in humans, all the components of the signalling pathway (Reelin, Dab1, VLDLR and ApoER2) are present in subsets of Cajal–Retzius cells. In the mouse cortical plate, VLDLR and ApoER2 are present from E15 to postnatal stages; in human cortical plate they are most prominent at ≈ 20 gestational weeks. In mice, cerebellar Purkinje cells only express VLDLR whereas in humans they express both VLDLR and ApoER2. Mitral cells of the mouse olfactory bulb are ApoER2-positive and VLDLR-negative. In sum, the receptor expression patterns are similar in the human and mouse cortical plate but differ in Cajal–Retzius and Purkinje cells, which in humans express additional components of the reelin–Dab1 pathway.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of communication 50 (2000), S. 0 
    ISSN: 1460-2466
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Media Resources and Communication Sciences, Journalism
    Notes: This paper reports the outcome evaluation of a gun safety video intervention. Guided largely by the extended parallel process model, the video, Bullet ‘Proof’ - The Case for Gun Safety' focuses primarily on (a) knowledge of 6 gun safety practices, (b) susceptibility to accidental gunshot injuries and death, severity of gunshot injuries, (d) response efficacy, and (e) self-efficacy. The video was shown to 175 individuals in 7 hunter safety classes and evaluated in a field experiment using a posttest-only control-group design with random assignment. Compared to the control group, the experimental group listed significantly more gun safety practices, perceived greater susceptibility to accidental gun injuries, perceived gun injuries to be more severe, and perceived greater response efficacy toward some of the recommended gun safety practices. Further, all of the recommended gun safety practices received high self-efficacy and behavioral intention ratings. Finally, the video itself scored high on all measured positive attributes, and low on all measured negative attributes.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 145 (2000), S. 2047-2059 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  Bovine herpesvirus type 1 (BHV-1) causes respiratory and genital diseases in cattle, whereas the closely related BHV-5 can induce severe meningoencephalitis in calves. To characterize BHV-5 glycoprotein C (gC5) within the backbone of BHV-1, three consecutive recombinant viruses were constructed: A deletion mutant (rBHV-1ΔgC blue) with gC1 replaced by the lacZ gene, an exchange mutant (rBHV-1gC5) with the lacZ of BHV-1ΔgC blue exchanged by gC5, and a rescue mutant (rescue BHV-1) from rBHV-1gC5 with an additional XbaI site in gC1. The recombinant and wildtype viruses were characterized on MDBK cells. Although no significant differences were observed in growth behaviour and entry kinetics, rBHV-1gC5 showed a distinct phenotype in a heparin blocking assay. The gC5 was able to transfer the heparin binding phenotype of BHV-5 to BHV-1. This indicates that gC1 and gC5 differ in their receptor binding qualities, which might modulate the ability of the viruses to spread within the central nervous system.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 15 (1962), S. 271-281 
    ISSN: 0001-5520
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 201 (1964), S. 315-315 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Psammechinus miliaris, 16 h gastrula, 2 cells of the oral field. n, nucleus; m, mitochondrium; y, yolk sphere. The arrows indicate the elongated tips of the inner surface of the cells, (× c. 11,700) Examining thin sections of 16-h gastrulse of Psammech-inus miliaris in search of specific ...
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 193 (1962), S. 941-942 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] CHROMATOGRAPHY on adsorbent-coated glass strips or plates is frequently used as a qualitative analytical method. We have modified the techniques described by Kirchner1 and Stahl2 to make it applicable for preparative purposes. The method compares favourably with column chromatography in many ...
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. Morphological manifestations of the chromosomal metabolism have been found in the first spermatocyte nucleus of Drosophila melanogaster. These “metabolic structures” include several types of well defined components, among which the „tubuli“ and the „reticular elements“ are most conspicuous. The metabolic nature of these elements follows from their phase specifity and from cytochemical data. 2. Masses of tubuli of 300–400 Å diameter are found all over the meiotic prophase chromosomes in the spermatocyte nucleus, but not in the spermatogonial nucleus. The reticular elements appear somewhat later and usually form a single group. Both types of metabolic structures are decomposed during diakinesis when they separate from the chromosomes. 3. The tubuli are mainly composed of a basic protein. In addition they seem to contain RNA. The presence of DNA in small concentration can not yet be excluded. 4. The chromosomal origin of the tubular as well as the reticular elements follows not only from the observed contact with the chromosomes but also from the fact that spermatocyte nuclei of X/O-males of Drosophila melanogaster do not contain these components. This shows that the Y-chromosome is involved. 5. The role of the Y-chromosome in the formation of the metabolic structures has been further elucidated by studying males with partial Y-chromosomes, such as YS, YL, and Y″. Spermatocytes with the long arm of the Y (X/YLc) as a rule contain tubular and reticular elements in nearly normal quantity. X/YS and X/Y″ testes show a highly variable pattern. Some spermatocyte nuclei resemble the X/O-type while the rest represent all intermediate stages between the X/O- and the X/YL-type. 6. The lack of tubuli in X/O or in X/YS and X/YL spermatocyte nuclei is always correlated with the appearance of crystal needles in the nucleus as well as in the cytoplasm. Only very rarely in X/YS spermatocytes is an intranuclear crystal found together with a small amount of tubuli. The X/O crystal needles persist during spermatogenesis and are still found in sperm bundles. The crystal material seems to be a protein which is different from the tubular protein. 7. The possibilities of the involvement of the Y-chromosome in the formation of the metabolic chromosomal structures are discussed. It seems probable that tubuli represent a highly modified state of the Y-chromosome, or parts of this chromosome. The formation of protein crystals in X/O-spermatocytes indicates the presence of a biochemical block. The relation to fertility i.e. sperm motility is unclear. X/YL males do not produce motile sperms although tubuli are regularly present in spermatocyte nuclei.
    Type of Medium: Electronic Resource
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