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  • Artikel: DFG Deutsche Nationallizenzen  (2)
  • 1995-1999  (2)
  • Anti-viral activity  (1)
  • Cytokine  (1)
  • Passive filter  (1)
Datenquelle
  • Artikel: DFG Deutsche Nationallizenzen  (2)
Materialart
Erscheinungszeitraum
  • 1995-1999  (2)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Artificial life and robotics 3 (1999), S. 86-89 
    ISSN: 1614-7456
    Schlagwort(e): System design ; Emergence ; Evolutionary computation ; Passive filter ; Multi-link robot
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract An emergent approach for the design of artifacts (artificial systems) is proposed. First, the system design process is reformulated in the framework of set and mapping theory, and the design problem is defined as an inverse mapping from the set of specifications depending on the environment to the set of components and their connections. The inverse problem can be solved by the iteration of forward mapping. Next, the problem is classified from the viewpoint of the specifications and the environment. The concepts of evolution, adaptation, learning, and coordination can be related to classified problems. Emergent design procedure is defined in the framework of these concepts, in particular by taking evolutionary computing techniques into account. Two examples are shown: the first is a design of complex linear passive filters, and the other is a design of multilink moving robots.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 254 (1997), S. 158-162 
    ISSN: 1434-4726
    Schlagwort(e): Idiopathic sudden sensorineural hearing loss ; Interferon-α treatment ; Anti-viral activity ; 2′-5′ oligoadenylate synthetase ; Cytokine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We have employed alpha-interferon (IFN-α), an anti-viral agent, in the treatment of severe idiopathic sudden sensorineural hearing loss (ISSHL). Forty-two patients were studied and had an average hearing ability of ≥ 70 dB before treatment. We also examined 2′-5′ oligoadenylate synthetase (2,5A-S) activity, one of the parameters indicating anti-viral activity of IFN, to investigate the relationship between the suppression of viral proliferation and prognosis and explain the pathogenesis of ISSHL. Complete recovery was found in 27 patients (64.3%) after IFN therapy. Increased 2,5A-S activity was observed on the 3rd day of IFN therapy in 24 of the 27 patients who completely recovered. No severe adverse events were reported after IFN therapy. Findings suggest that IFN therapy may be effective and safe in the treatment of ISSHL and calls for further investigation.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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