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Selection of Mixed Cultures for Meat Fermentation (1989)

HOULE, J.-F. ; LAFRANCE, M. ; JULIEN, J.-P. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Journal of food science 54 (1989), S. 0

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ISSN: 1750-3841

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology

Notes: Strains of Pediococcus cerevisiae, Pediococcus acidilactici, Lactobacillus plantarum, Lactobacillus casei and Micrococcus varians were studied with the aim of preparing mixed cultures of compatible strains for meat fermentations. Addition of 0.18% nitrite was slightly inhibitory while addition of 7% of a spice mix proved stimulatory. Antibiosis was observed between lactobacilli and pediococci. Micrococcus varians did not produce inhibitory substances toward other cultures and was insensitive to bacteriocins produced by the lactobacilli or the pediococci. Antibioses observed using disk assays were confirmed in mixed acidification trials, and mixes of some fast-acidifying strains were unsuccessful.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2621.1989.tb07894.x

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Polyadenylic-polyuridylic acid plus locoregional and pelvic radiotherapyversus chemotherapy with CMF as adjuvants in operable breast cancer (1991)

Lacour, J. ; Laplanche, A. ; Delozier, T. ; [et al.]

Springer

Breast cancer research and treatment 19 (1991), S. 15-21

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ISSN: 1573-7217

Keywords: adjuvant treatment ; breast cancer ; chemotherapy ; immunotherapy ; radiotherapy ; randomized trial

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary In this study, patients with operable breast cancer T2 or T3, treated by mastectomy + axillary dissection and with invaded axillary nodes (N+), were randomized to receive either: 1) postoperative locoregional and pelvic radiotherapy (RX) and Poly(A).Poly(U) (AU), 60 mg IV once a week for 6 weeks, or 2) CMF (cyclophosphamide 100 mg/sqm P.O. on days 1–14, methotrexate 40 mg/sqm IV on day 1 and 8, fluorouracil 600 mg/sqm IV on day 1 and 8; monthly cycle, for 6 months. Between March 1982 and December 1985, 517 patients were enrolled, 257 of whom were treated by RX + AU and 260 with CMF. The main clinical, pathological and prognostic characteristics were equally distributed in the two groups. The present analysis was conducted after a mean follow-up of 69 months (S.D.=13). There was no significant difference in overall survival (OS) between the two groups (test adjusted by center and menopausal status); the five-year OS rate was 74% in the RXAU group and 77% in the CMF group. Relapse-free survival (RFS) was significantly higher (p=0.05) in the RXAU group compared to the CMF group; the five-year RFS rates were 57% and 46% in the two groups respectively. This short, well-tolerated combined RXAU treatment appears to be as efficient as CMF and might offer an alternative to chemo- or hormonotherapy, in case of contraindications to these treatments.