ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Sortierung

Digitale Medien

Is the dopaminergic system involved in the central effects of nicotine in mice? (1993)

Damaj, M. I. ; Martin, B. R.

Springer

Psychopharmacology 111 (1993), S. 106-108

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1432-2072

Schlagwort(e): Nicotine ; Dopamine antagonists ; Hypoactivity ; Hyperactivity ; Antinociception ; Mice

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Pretreatment with ineffective doses of the D1 antagonist SCH23390 but not the D2 antagonist sulpiride reduced hyperactivity induced by nicotine in mice habituated to the test cage. On the other hand, the D1 and D2 antagonists were ineffective in blocking nicotine-induced hypoactivity in naive mice. Finally, SCH23390 and sulpiride did not block the antinociception induced by nicotine. Our data indicate that the dopamine receptors D1 and D2 are not involved in all the central effects of nicotine in mice, but seems to be a substrate for locomotor activation induced by nicotine under specific experimental conditions.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02257415

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer