ISSN:
1432-1971
Keywords:
Doppler echocardiography
;
Microspheres
;
Cardiac output
;
Premature baboon
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Pulsed-Doppler echocardiography (PDE) is a useful noninvasive method for determining left ventricular output (LVO). However, despite increasingly widespread use in neonatal intensive care units, validation studies in prematures with cardiopulmonary disease are lacking. The purpose of this study was to compare radiolabeled microsphere (RLM) and PDE measurements of LVO, using the critically ill premature baboon as a model of the human neonate. Twenty-two paired RLM and PDE measurements of LVO were obtained in 14 animals between 3 and 24 h of age. Average PDELVO was 152 ml/min/kg (range, 40–258 ml/min/kg) compared to 158 ml/min/kg (range, 67–278 ml/min/kg) measured by RLM. Linear regression analysis of the paired measurements showed good correlation with a slope near unity (y=0.94x+4.20,r=0.91, SEE=25.7 ml). We conclude that PDE determinations of LVO compare well with those measured by RLM in the premature baboon. PDE appears to provide a valid estimate of LVO and should be useful in human prematures with cardiopulmonary distress.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02238410
Permalink
