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Does pertussis infection induce manifestation of allergy? (1993)

Schuster, A. ; Hofmann, A. ; Reinhardt, D.

Springer

Journal of molecular medicine 71 (1993), S. 208-213

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ISSN: 1432-1440

Keywords: Allergy ; Whooping cough ; Pertussis toxin ; IgE

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary To evaluate whether pertussis induces the development of allergy, a prospective study was performed in 25 children aged 0.8–12.2 years. The patients underwent allergy diagnostics during pertussis infection and at a follow-up visit 8–14 months later. Diagnostic criteria included the medical history of the patients and their families, a modified skin prick test, measurement of serum IgE and radio-allergosorbent test screening for specific sensitizations. At the time of pertussis, serum IgE concentration in the study group was 62+ 30 kU/ml. At the follow-up visit, there was a significant increase in serum IgE to 137 ± 51 kU/ml, which was also significantly higher than IgE in an age-matched control group. Children at a significantly higher risk for developing IgE increase or new allergic sensitizations were those with a family history of allergy or potentially allergic disease in their personal history. Our results indicate that pertussis may induce IgE production in affected children.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00180103

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Collective and molecular dynamics in ferroelectric liquid crystals: from low molar to polymeric and elastomeric systems (1992)

Kremer, F. ; Schönfeld, A. ; Hofmann, A. ; [et al.]

New York, NY : Wiley-Blackwell

Polymers for Advanced Technologies 3 (1992), S. 249-255

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ISSN: 1042-7147

Keywords: Ferroelectric liquid crystals ; Polymers ; Dielectric spectroscopy ; Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Notes: Broadband dielectric spectroscopy delivers in the frequency range from 10 Hz to 1010 Hz two collective dielectric loss processes (soft and Goldstone modes) and one molecular relaxation (β-relaxation). The soft mode and Goldstone mode are assigned to the fluctuation of the amplitude and the phase of the helical superstructure. The β-relaxation corresponds to the libration (hindered rotation) of the mesogene around its long molecular axis. At the SmA-SmC* phase transition this process does not split or broaden, and the temperature dependence of its relaxation rate does not show any deviation from an Arrhenius-like behavior. Its dielectric strength does not decline at the SmA-SmC* phase transition. These experimental findings are in contrast to the common explanation of the origin of the saturation polarization (“induced spontaneous polarization”), which is based on the existence of a “free” rotation inside the SmA phase and its strong hindrance in the ferroelectric SmC* phase. Furthermore, the high frequency results require a reformulation for the (generalized) Landau theory as applied to the SmA-SmC* phase transition. In comparing low molar mass and polymeric (elastomeric) FLC, the collective and molecular dynamics are qualitatively similar, independent of the molecular architecture (e.g. side-chain, combined main- and side-chain or crosslinked systems).

Additional Material: 13 Ill.