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  • Articles: DFG German National Licenses  (2)
  • 1990-1994  (2)
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  • Articles: DFG German National Licenses  (2)
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Year
  • 1
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In echo virus type 25/JV-4 the shut off of host cell protein synthesis took significantly longer and the kinetics of the synthesis of viral proteins and viral RNA occurred much later than in the poliovirus. However, these characteristics impaired neither polyprotein processing nor virus production in the JV-4 strain. In contrast the two wild strains M.1262 and Th.222 had a lower virus yield than strain JV-4. The presence of a high Mr protein in the pattern of viral proteins of wild strains suggested that a defect in the polyprotein processing was responsible for the decreased virus yield. The infectious cycle of strain Th.222 differed from that of strains JV-4 and M.1262 in the rapid inhibition of host cell translation and the extent of viral protein synthesis. The sensitivity to actinomycin D was also investigated. Strain M.1262 was found to be insensitive. The virus yield of strains JV-4 and Th.222 was three- and fourfold lower respectively in the presence of actinomycin D. This sensitivity to the antibiotic was observed during viral RNA synthesis in strain JV-4 and during viral protein synthesis in strain Th.222. These results suggest that cellular factors are involved in the replication of echo virus type 25 strains in MRC5 cells.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Properties of proton diffractive dissociation have been investigated for four-prong final states in proton-proton reactions at 360 GeV/c, in particular forpp→ppπ +π− mπ 0(m=0,1,2). Mass distributions and decay angular distributions are given. The decay of the diffractive system is seen to be very anisotropic, and largep T is suppressed at higher masses. It is found that the “pomeron” couples with a single valence quark of the incident proton, but indications for a diquark-pomeron coupling are also found. Similarities with fragmentation in lepton-hadron deep inelastic scattering are underlined.
    Type of Medium: Electronic Resource
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