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  • Articles: DFG German National Licenses  (4)
  • 1990-1994  (4)
  • 1
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] LCa.ll cells9 were cotransfected with various combinations of expression plasmids for a2, ft and y subunit cDNAs. Northern blot analyses of poly(A)+ RNA preparations from the various transfected cell lines (Fig. la, b) confirmed that the parental LtkT cells expressed no transcripts for the skeletal ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Evolutionary ecology 5 (1991), S. 415-427 
    ISSN: 1573-8477
    Keywords: Parental investment ; egg size ; environmental uncertainty ; phenotypic variance ; life history variation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Using a model that allows the mean and variance of investment by parents in offspring to evolve in response to change in degree of temporal environmental variation, this paper shows that both parental investment parameters should increase with increases in temporal variation. If offspring receiving greater parental investment are viable over a broader range of environmental conditions, then increased temporal environmental variation can select for increases in parental investment. The variance in parental investment also may increase with increases in temporal variation, but there is a threshold level of temporal variation that must be exceeded before variance in parental investment is adaptive. Thus phenotypic variance in parental investment is not adaptive in all temporally varying environments. Further, increased overlap among generations reduces the expected effects of temporal variation on the mean and variance in parental investment. Thus a negative correlation between length of reproductive life and both measures of investment is expected. There is support for the predictions of this model in some animal groups, but not among plants. Possible reasons for the lack of support among plants are discussed and directions for future research aimed at distinguishing adaptive and maladaptive phenotypic variance in parental investment are suggested.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Previous studies have demonstrated that His 12 plays a major role in the pH-dependent stability of the helix formed by the isolated C-peptide (residues 1-13 of ribonuclease A). Here, amino acid replacement experiments show that His 12+ stabilizes the C-peptide helix chiefly by interacting with Phe 8. The Phe 8 ⃛ His 12+ ring interaction is specific for the protonated form of His 12 (His 12+) and the interaction is not screened significantly by NaCl, unlike the charged group ⃛ helix dipole interactions studied earlier in C-peptide. Analogs of C-peptide that are unable to form the Phe 8 ⃛ His 12+ interaction show large increases in helix content for Phe → Ala and His → Ala. Therefore, the helical tendencies of the individual residues Phe, His, and Ala are important in determining the result of a replacement experiment. Since the side chains of Phe 8 and His 12 probably interact within the N-terminal helix of ribonuclease A, the existence of the Phe 8 ⃛ His 12+ interaction in the isolated C-peptide helix adds to the evidence that the C-peptide helix is an autonomous folding unit.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 10 (1990), S. 259-284 
    ISSN: 0271-2091
    Keywords: Finite differencing ; Iterative methods ; Convection-diffusion ; Boundary layer ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A method is developed to solve elliptic singular perturbation problems. Examples are presented in one and two dimensions for both linear and non-linear problems. In particular, examples are presented for fluid flow problems with boundary layers. In the one-dimensional case an approximating equation is developed using just three points. The method first presented is a fourth-order approximation but is extended to become a higher-order method. Results are included for the fourth-, sixth-, eighth- and tenth-order methods.The results are first compared with results found by Segal in an article about elliptic singular perturbation problems. The elliptic singular perturbation problems are compared with a method by Il'in and also with central and backward difference schemes from Segal's article. There was only one case where the results in Segal's paper were as accurate as the results presented in this paper. However, in this case the method used by Segal did not give accurate values for a second problem presented. The results are also compared with results given by Spalding and by Christie.The method of this paper was also tested on the solution of some non-linear diffusion equations with concentration-dependent diffusion coefficients. The results were superior to results presented by Lee and by Schultz. Finally, the method is extended to several two-dimensional problems.The method developed in this paper is accurate, easy to use and can be generalized to other problems.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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