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  • Articles: DFG German National Licenses  (2)
  • 1985-1989  (1)
  • 1980-1984  (1)
  • Autochthonous colonic tumors  (1)
  • Hürthle cell tumor  (1)
Source
  • Articles: DFG German National Licenses  (2)
Material
Years
  • 1985-1989  (1)
  • 1980-1984  (1)
Year
  • 1
    ISSN: 1432-1335
    Keywords: Autochthonous colonic tumors ; N-nitrosoacetoxymethyl-methylamine ; 1,2-Dimethylhydrazine ; 5-Fluorouracil ; Ftorafur ; CGP 6809 ; CGP 15'720A
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Colonic tumors were induced in male Sprague-Dawley rats by ten applications of 2 mg/kg/week N-nitrosoacetoxymethyl-methylamine (AMMN) or by three applications of 100 mg/kg/month 1,2-dimethylhydrazine (1,2-DMH). Application of AMMN and 1,2-DMH induced selective colonic tumors in 97% and 29–42% of the initial animals, respectively. Colonic-tumor-bearing animals were subjected to monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A. No cures were achieved. The different therapies did not exert any clear influence on the survival time of animals, except for animals pretreated with AMMN and then subjected to ftorafur therapy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 594-594 
    ISSN: 1435-2451
    Keywords: Oncocytoma ; Hürthle cell tumor ; Onkocytom ; Onkocytäres Carcinom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Dignität der Onkocytome der Schilddrüse ist umstritten. Von 1965 bis 1973 wurden an der Chirurgischen Universitätsklinik München sechs Patienten mit einem onkocytären Carcinom und zwölf Patienten mit einem benignen Onkocytom operiert. Bei den histologisch gesicherten, benignen Onkocytomen trat im Beobachtungszeitraum, von durchschnittlich 11 Jahren, kein Lokalrezidiv und keine Metastase auf. Wir empfehlen daher die primäre Hemithyreoidektomie bei benignen Onkocytomen. Die Thyreoidektomie bleibt den onkocytären Carcinomen vorbehalten.
    Notes: Summary There is still a dispute about the malignant potential of Hürthle cell tumors of the thyroid. In our clinic 6 patients with Hürthle cell carcinoma (HCC) and 12 patients with benign Hürthle cell adenoma (HCA) have been treated between 1965 and 1973. None of the patients with HCA showed a recurrence over a mean period of 11 years, although only subtotal resection had been carried out. We therefore recommend total lobectomy for HCA. Total thyroidectomy should only be carried out in cases involving malignancy.
    Type of Medium: Electronic Resource
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