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  • Articles: DFG German National Licenses  (3)
  • 1985-1989  (3)
  • Cebocephaly  (1)
  • Immunohistochemistry  (1)
  • Intermediate filament  (1)
  • Lymphocytic adenohypophysitis  (1)
Source
  • Articles: DFG German National Licenses  (3)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 77 (1988), S. 33-38 
    ISSN: 1432-0533
    Keywords: Rathke's cleft cyst ; Immunohistochemistry ; Pituitary hormones ; Intermediate filament ; Squamous metaplasia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An immunohistochemical study was made of ten cases of asymptomatic and three cases of symptomatic Rathke's cleft cyst. The cysts in the asymptomatic cases had monolayer columnar or cuboidal epithelium. Within the epithelium, cells which were positive for at least one of the pituitary hormones were found. The rate of positive reactions for these six pituitary hormones was between 70% and 100%. In contrast, the cysts in the symptomatic cases had an epithelium which was partly stratified squamous and partly squamous epithelium, and none of the pituitary hormones were found in them. Therefore, when a Rathke's cleft cyst enlarges to the extent that clinical symptoms are produced, we consider that changes have already occurred in structure and function of the cyst epithelium. In addition, we believe there is a tendency for monolayer epithelia to undergo squamous metaplasia and for cells which are positive for pituitary hormones to change into non-granulated cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 29 (1987), S. 488-492 
    ISSN: 1432-1920
    Keywords: Pituitary tumor ; Pregnancy ; Lymphocytic adenohypophysitis ; Hypopituitarism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have encountered a case of a pituitary mass which emerged and enlarged during pregnancy in a 29-year-old woman. On CT scaning the mass disappeared over the course of four months postpartum and was followed by pituitary hypofunction. The hypofunction was restricted to ACTH, GH, and PRL. The visual field defects, bitemporal hemianopsia, disappeared with disappearance of the pituitary mass on CT scanning, indicating that such deficits during this period were reversible. Based on the clinical course and laboratory data, this case is thought to have been lymphocytic adenohypophysitis. It was concluded that among pituitary tumors developing during pregnancy there are some such cases which do not require surgical therapy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 3 (1987), S. 251-254 
    ISSN: 1433-0350
    Keywords: Holoprosencephaly ; Cebocephaly ; 7q deletion ; Aberrant adenohypophysis ; Multiple congenital anomalies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An autopsy case of cebocephaly-holoprosencephaly at 27 weeks' gestation is reported. Chromosome analysis revealed a 46, XX,-7, +der(7), t(7; 13) (q32; q34) pat karyotype. Pathological examination disclosed a hypoplastic aberrant adenohypohysis, in which immunohistochemical localization of four anterior pituitary hormones (ACTH, GH, PRL, TSH-β) was demonstrated. Malformation of the pituitary gland in holoprosencephaly can include ectopic adenohypophysis as well as pituitary dysgenesis, so a careful search for adenohypophysis should be made in future cases for a better understanding of endocrine dysgenesis associated with holoprosencephaly.
    Type of Medium: Electronic Resource
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