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  • Articles: DFG German National Licenses  (3)
  • 1985-1989  (3)
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  • Articles: DFG German National Licenses  (3)
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Year
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  • 1
    Electronic Resource
    Electronic Resource
    A model of hemopoietic stress in a lactate dehydrogenase mouse mutant with hemolytic anemia (1986)
    Springer
    Annals of hematology 52 (1986), S. 179-183 
    Details
    ISSN: 1432-0584
    Keywords: Lactate dehydrogenase mutation ; Hemolytic anemia ; Hemopoietic regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A codominantly inherited mutation of the lactate dehydrogenase (LDH) in the C3H mouse causes a severe hemolytic anemia in homozygous mutants, whereas viability and fertility are close to normal. Investigation of multipotent hemopoietic stem cells (CFU-S), myeloid (GM-CFC) and erythroid progenitors (BFU-E, CFU-E) in femur and spleen indicates a general shift from bone marrow to splenic hemopoiesis. In terms of total body hemopoiesis, however, the BFU-E pool is 1.4- and the CFU-E pool 19-fold enlarged, whereas CFU-S and GM-CFC show little or no deviation from normal. It is concluded that this mouse mutant is an appropriate model of long-term hemopoietic stress showing that compensation in this severe hemolytic anemia is achieved primarily by an increase of the number of the most mature erythroid progenitors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320534
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    Paper (German National Licenses)
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  • 2
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    Unknown
    Attitudes toward women in Northern Ireland (1987)
    Worcester, Mass. : Periodicals Archive Online (PAO)
    Journal of Social Psychology. 127 (1987) 531-533 
    Details
    ISSN: 0022-4545
    Topics: Psychology , Sociology
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1143-1987-127-00-000055
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of variance approximation techniques for non-linear photosynthesis—irradiance models (1987)
    Springer
    Marine biology 95 (1987), S. 209-215 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Parameters derived from photosynthesis-irradiance (P-I) models, although often empirical in nature, are useful indicators of the photoadaptive state of phytoplankton in culture and in situ. However objective criteria for determining significant changes in P-I curves are rarely provided, because confidence intervals for parameters of non-linear models are not estimated easily. Examination of least-squares residuals in parameter space and Monte Carlo approaches have been used to estimate confidence regions around parameter values, but the computationally intensive nature of these methods has prevented their routine application. We present an alternative method of estimating confidence intervals for parameters of P-I curves that runs quickly on a microcomputer and is easily combined with common parameter-estimation routines. This algorithm was tested using a 3-parameter P-I model and curves describing a wide range of photoadaptive states, with different numbers of observations and different amounts of inherent variability. The method produced results comparable to the Monte Carlo technique. This analysis makes it possible to specify the sample size required to define parameters with acceptable confidence as a function of data variance and photoadaptive state. In most reasonable situations, 25 observations are sufficient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00409007
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    Paper (German National Licenses)
    Fulltext
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