ISSN:
1432-1246
Keywords:
Phenol
;
Chlorophenols
;
Urine
;
Excretion
;
Exposed workers
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary An analytical method is described which has suitable sensitivity and specificity for analyzing urine samples from workers who are exposed to chlorinated phenols. The phenolic compounds are separated by steam distillation and then extracted into isopropyl ether. Without derivatizing the material, it is analyzed by gas chromatography on a 180 cm x 2 mm i.d. glass column containing 60/80 mesh Tenax GC (ENKA NV, The Netherlands) using flame ionization detectors. The detection limits in urine range from 0.1 mg/l urine for phenol to 1 mg/l for the di- and trichlorophenols. The coefficient of variation for each component is less than 4%. The naturally occurring metabolites cresol and 4-heptanone are also isolated and can be quantified by this method.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00378096
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