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  • Articles: DFG German National Licenses  (2)
  • 1980-1984  (1)
  • 1975-1979  (1)
  • Amphibian  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 185 (1978), S. 99-104 
    ISSN: 1432-041X
    Keywords: Amphibian ; Grey crescent ; Colchicine ; Cytochalasine B
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The effects of colchicine and cytochalasin B on grey crescent formation in frog (Rana pipiens) and toad (Bufo arenarum) eggs were determined. Colchicine prevented the appearance of the grey crescent, but this inhibition was not due to the absence of an aster. Cytochalasin B did not inhibit grey crescent formation, nor did it inhibit certain activation events such as cortical granule breakdown or cortical contraction. Cytochalasin B caused a detachment of the cortex from the cytoplasm and induced the formation of a morphological grey crescent in non-activated eggs. The results suggest that microtubules may play several roles in grey crescent formation and that a change in the attachment of the cortex to the cytoplasm may also be involved.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 189 (1980), S. 73-76 
    ISSN: 1432-041X
    Keywords: Ultraviolet irradiation ; Amphibian ; Grey crescent ; Embryology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Work by others has shown that ultraviolet (UV) irradiation of the vegetal half of the uncleaved frog egg causes defects in neural development. We find that the earliest effect of irradiation ofRana pipiens eggs is to prevent grey crescent formation, the first indication of dorso-ventral polarization of the egg. The UV effect on the grey crescent and on neural development shows similarities in timing, dose-responses, and reversal by cold. We suggest that the UV effect on neural morphogenesis may be caused by the inhibition of cortical-cytoplasmic movement involved in grey crescent formation.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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