ISSN:
1434-4475
Keywords:
Ketol-isomerization
;
Tricyclic diterpene
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The syntheses of the pleuromutilin derivatives12 and16 are described. Both compounds on treatment with base rearrange to the isomeric ketol13. The results of the deuteration experiment as well as the kinetic measurements are in agreement with the hypothesis of an intramolecular 1,4-hydride shift.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00798448
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