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  • Articles: DFG German National Licenses  (2)
  • 1980-1984  (2)
  • Chronic idiopathic thrombocytopenic purpura  (1)
  • Hematopoietic dysplasia  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The preleukemic syndromes (hematopoietic dysplasia) in childhood (1980)
    Springer
    European journal of pediatrics 133 (1980), S. 5-10 
    Details
    ISSN: 1432-1076
    Keywords: Preleukemia ; Hematopoietic dysplasia ; Refractory anemia ; Myeloproliferative disease ; Acute nonlymphocytic leukemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The preleukemic syndrome or hematopoietic dysplasia is a marrow stem-cell disorder with clinically recognizable hematologic abnormalities which precede the development of acute nonlyphocytic leukemia. Its occurrence in childhood is extremely rare; seven “true” cases who fulfill all the criteria for the disorder have been reported until now. The preleukemic syndrome is generally characterized by peripheral cytopenia with fairly specific morphologic abnormalities in cell differentiation. The hematological and clinical features permit recognition of preleukemia even before the development of overt leukemia. Experimental data indicate that preleukemia is an “early” leukemic syndrome in which hematopoietic cell differentiation becomes progressively impaired with termination in the nearly complete maturation block which is characteristic of acute myelogenous leukemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444747
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The place of intravenous immunoglobulin (IgG i.v.) therapy in thrombocytopenia (1984)
    Springer
    Annals of hematology 48 (1984), S. 409-413 
    Details
    ISSN: 1432-0584
    Keywords: Acute postinfectious ITP ; Chronic idiopathic thrombocytopenic purpura ; Immunoglobulin therapy ; Steroid therapy ; ITP in pregnancy ; Neonatal thrombocytopenia ; Neonatal isoimmune thrombocytopenia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Acute ITP following infection in children has a high rate of spontaneous remission. Since the platelet count is not uncommonly profoundly depressed, ITP is associated with a mortality of around 1%. The aim of treatment in ITP is to prevent bleeding. As a rule, this can only be achieved by normalizing the platelet count. Intravenous immunoglobulin offers certain advantages over conventional steroid therapy. Moreover, two out of three patients with chronic ITP respond to IgG i.v. The characteristic features of ITP in pregnancy, thrombocytopenia in babies born to mothers with ITP and neonatal isoimmune thrombocytopenia are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319973
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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