ISSN:
1432-1041
Keywords:
ibopamine
;
hyperprolactinaemia
;
dopamine agonist
;
prolactin inhibition
;
prolactin-secreting adenoma
;
female volunteers
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary The effect of the diisobutyric ester of N-methyldopamine (Ibopamine) on plasma prolactin levels was investigated in normoprolactinaemic subjects and in hyperprolactinaemic patients with prolactin-secreting tumours or idiopathic hyperprolactinaemia. In hyperprolactinaemic states oral Ibopamine 50 mg induced a significant decrease in elevated plasma prolactin (PRL) levels, 30, 60 and 90 min after administration. The peak effect occurred at 90 min when the mean PRL level was 61% of its basal values.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00544029
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