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  • Articles: DFG German National Licenses  (2)
  • 1980-1984  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 93 (1984), S. 193-198 
    ISSN: 1437-1596
    Keywords: Hematoma ; Heme oxygenase activity ; Biliverdin reductase ; Hämatome, Vitalzeitperioden ; Hämioxygenaseaktivität ; Biliverdin-Reductase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Aktivitäten von Hämi-Oxygenase und Biliverdin-Reductase wurden in subcutanen (s.c.) Hämatomen bei Ratten nach verschiedenen Vitalzeitperioden bestimmt. Die postmortale Stabilität der hämi-degradierenden Enzyme wurde ebenfalls untersucht, indem die Ratten mit vitalen Hämatomen 1–5 Tage bei +4°C bzw. +22°C gehalten wurden. Eine zehnfache Steigerung der Hämi-Oxygenaseaktivität über das Ausgangsniveau hinaus wurde in Hämatomen von 2–9 Tagen Alter wahrgenommen, wenn die Proben unmittelbar nach dem Tod entnommen waren. Biliverdin-Reductase wies nur geringfügige Veränderungen auf. Postmortal begann die Hämi-Oxygenaseaktivität in den Hämatomen bei +22°C unmittelbar bzw. bei +4°C vom zweiten Tag an herabzugehen.
    Notes: Summary The activities of heme oxygenase and biliverdin reductase were determined in subcutaneous (s.c.) hematomas of rats after different periods of vital time. The postmortem stabilities of the heme-degrading enzymes were also studied by keeping the rats with vital hematomas for 1–5 days at temperatures of +4°C and +22°C. A tenfold increase of heme oxygenase activity over the starting level was observed in 2–9-day-old vital hematomas, when the specimens were taken immediately after death. Biliverdin reductase showed only negligible changes. Postmortally, heme oxygenase activity started to decrease in hematomas immediately at +22°C and from day 2 on at +4°C.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 46 (1980), S. 87-92 
    ISSN: 1432-1246
    Keywords: Hydrogen sulfide ; Cytochrome oxidase ; Cumulative inhibition ; Neurotoxic effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Adult female NMRI mice exposed four times to 100 ppm hydrogen sulfide vapour for 2 h at 4-day intervals showed increasing inhibition of the cerebral cytochrome oxidase activity. Cerebral RNA decreased significantly after the fourth exposure. This change was accompanied by the reduced orotic acid uptake in the RNA fraction. At the same time, 2′,3′-cyclic nucleotide 3′-phosphohydrolase activity used as a marker for glia increased. Acetylcholine esterase activity remained unchanged. The initial exposures also caused an increase in the superoxide dismutase activity and an increase in the glutathione concentration. The latter effects were abolished in the third and fourth exposures. The present data seem to indicate that the biochemical effects of repeated subclinical hydrogen sulfide intoxications are cumulative.
    Type of Medium: Electronic Resource
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