ISSN:
1432-2072
Keywords:
Psychopharmacology
;
Diphenylhydantoin
;
Anxiety
;
Hostility
;
Psychiatric Status Rating Scales
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In a six-week double-blind cross-over study, DPH, 100 mg, t.i.d., was found to be markedly more effective than DPH, 5 mg, t.i.d., used as a placebo, in reducing symptoms relating to anger, irritability, impatience, and anxiety. The psychoactive properties of DPH were demonstrated by both self-ratings and physician ratings of change. Improvement when changing from 5 mg to 100 mg was matched by worsening when changing from 100 mg to 5 mg. Patients in the controlled study were selected on the basis of the presence of symptoms of anger, irritability, and anxiety, a social class more typical of private patients than clinic patients, and a Barron Ego Strength score of 40 or above. No undesirable side effects were encountered.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00402707
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