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  • Articles: DFG German National Licenses  (2)
  • 1970-1974  (2)
  • Chemistry  (1)
  • Renin Secretion  (1)
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  • Articles: DFG German National Licenses  (2)
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  • 1
    ISSN: 1432-2013
    Keywords: Renin Secretion ; Macula Densa ; Clopamide ; Ethacrynic Acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Renin secretion was studied in anesthetized dogs (Pentobarbital), after an injection of 5 mg/kg i.v. clopamide (10 animals) or ethacrynic acid (10 animals). Renin activity in venous renal blood (Boucher's method), renal blood flow (electromagnetic flowmeter), blood pressure, diuresis and natriuresis have been measured simultaneously. Basic renin secretion was 22,4±8,2 ng/g of kidney/min. During the 8 min following the ethacrynic acid injection renin secretion increased to 74,4±41,1 ng/g of kidney/min (p〈0.005). Within the same time it dropped to 11.1±6.8 ng/g of kidney/min (p〈0.005) after clopamide. These variations of renin secretion are related to the diuretic's action on the nephron, and depend on an endorenal mechanism. Ethacrynic acid suppresses the corticopapillary gradient while clopamide does not. We have not found any correlation between renin secretion and either natriuresis (mg/min) or diuresis (ml/min). But there is a connection (r=0.7367) between renin secretion after ethacrynic acid injection and sodium concentration in urine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 15 (1973), S. 85-91 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Flavor enhancing nucleotides may be produced by streptomycetes. Mutants of streptomyces 772 were found to produce, under ordinary fermentation conditions, considerable amounts of 5′-IMP and 5′-XMP, but only traces of 5′-GMP. This was probably due to the feedback inhibition of the end product GMP. It was shown that through suitable fermentation techniques it was possible to overcome this internal control mechanism, leading to increased yields of 5′-GMP.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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