ISSN:
1573-9686
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Technology
Notes:
Abstract Peak carotid and peak aortic flow acceleration were compared during a variety of cardiovascular interventions in seven acutely instrumented anesthetized (pentobarbital 30 mg/kg, iv) dogs. Flow velocity, recorded with electromagnetic sensors, was processed electronically to give acceleration and the ratio of peak carotid to peak aortic acceleration on a beat-by-beat basis. Occlusion of the left coronary artery, occlusion of the superior vena cava and intravenous administration of sodium bicarbonate and propranolol caused both peak carotid and peak aortic flow acceleration to decrease with little or no change in their ratio. Breathing 100% oxygen and iv infusions of metaraminol, levarterenol, isoproterenol, and acetyl choline and iv injection of serotonin, papaverine, and deslanoside increased peak carotid and peak aortic flow acceleration. The ratio of peak carotid to peak aortic acceleration did not change greatly except with isoproterenol, papaverine, and acetyl choline, when peak carotid flow acceleration increased more than peak aortic flow acceleration causing an increase in their ratio. Intravenous infusion of trimethaphan camphorsulfonate and injection of histamine caused peak carotid flow acceleration to increase and peak aortic flow acceleration to decrease with an increase in their ratio. Peak carotid flow acceleration may be of use as an indirect measure of myocardial mechanical performance except during potent peripheral vasodilation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02368489
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