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  • Artikel: DFG Deutsche Nationallizenzen  (4)
  • 32.70.J  (1)
  • 34.70  (1)
  • Dactyladenia barteri  (1)
  • Key words Small bowel transplantation  (1)
  • Nitrogen mineralization  (1)
Datenquelle
  • Artikel: DFG Deutsche Nationallizenzen  (4)
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  • 1
    ISSN: 1432-2277
    Schlagwort(e): Key words Small bowel transplantation ; Split tolerance ; FK 506 ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Functional long-term allograft survival after experimental small bowel transplantation (SBT) is limited by chronic rejection. Initial application of high-dose FK 506 has been shown to induce stable long-term graft function. In order to examine whether this long-term function is associated with donor-specific tolerance, we analyzed the functional status of recipient T cells in vivo and in vitro. One-step orthotopic SBT was performed in the allogeneic Brown Norway (BN)-to-Lewis rat strain combination. FK 506 was given daily at a dose of 2 mg/kg from days 0–5 in the rejection model and from days 0–9 in the long-term functional model. Mean survival time in the rejection model was 98 ± 2.8 days. Histological examination of these small bowel allografts disclosed signs of chronic rejection. In contrast, all animals of the long-term functional model survived long term ( 〉 250 days) without clinical signs of chronic rejection. The latter model, furthermore, produced evidence of donor-specific tolerance. Whereas heterotopic Dark Agouti (DA) hearts were rejected regularly within 7 days, BN hearts survived indefinitely ( 〉 70 days). In vitro, mixed leukocyte reactivity of CD4 + T cells was similarly strong against donor (BN) antigens as against third-party (DA) antigens. The split tolerance revealed by our in vivo and in vitro results enabled acceptance of both the small bowel allograft without signs of chronic rejection and of donor-specific heart allografts.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-0789
    Schlagwort(e): Dactyladenia barteri ; Leucaena leucocephala ; Lignin ; Nitrogen mineralization ; Nitrogen leaching
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Geologie und Paläontologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary The evolution of mineral and hydrosoluble organic N released from two soils differing in pH and treated with leaves of Leucaena leucocephala (0, 8.3, 16.7, and 33. g kg-1 soil), Dactyladenia barteri (syn. Acioa barteri; 0 and 16.7 g), and their mixtures was studied in the laboratory using the aerobic incubation-leaching method. N mineralization in untreated soils and in soils supplemented with 8.3 g leucaena leaves was 41–53% higher in the soil from Onne (pH 4.7) than in the soil from Ibadan (pH 6.2), but the organic N content was similar with these treatments in the leachates of the soils from both locations. The application of 16.7 or 33.3 g of either or both type of leaves reduced the rate of mineral N production during the first 4 weeks, particularly in soils treated with dactyladenia leaves (C:N=36). After this lag period, N mineralization proceeded at a faster rate in the soil from Ibadan treated with 16.7 or 33.3 g of leucaena leaves (C:N=12), even in the presence of dactyladenia leaves. In Ibadan soil, after 12 weeks, mineral N apprently derived from leaves of both dactyladenia and leucaena averaged 6.3% of the N applied, and organic N from leaves averaged 9.5%. The addition of dactyladenia and leucaena leaves did not increases the mineral N content in the acid soil from Onne but leaching of soluble organic N with addition of 16.7 or 33.3 g of leaves contributed an N-mineralizable pool of 5.9% of the N applied.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    ISSN: 1434-6079
    Schlagwort(e): 34.50.H ; 32.20.R ; 32.70.J
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract TheKβ spectra of molybdenum, palladium and lanthanum bombarded by 6.7 MeV/amu4He ions were measured with a transmission curved crystal spectrometer.L andM satellite lines were observed and resolved. Experimental energies are compared with those calculated with a MCDF program.M -shell ionization probabilities are deduced from the measured satellite intensity ratios and compared with theoretical (SCA) predictions. The experimental values are found to be higher than the calculated ones (by a factor of 2 for La and a factor of about 4 for Mo and Pd). The influence of coupling effects, electron wave functions, electron capture, electron correlation and target activation is discussed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    ISSN: 1434-6079
    Schlagwort(e): 34.50 ; 34.70
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract K α X-ray spectra were measured with a Du Mond type curves crystal spectrometer for42Mo and46Pd targets bombarded with oxygen ions at 5.5 MeV/u energy (i.e. at velocity closely matching those of the targetL-shell electrons). The distribution ofL-shell vacancies produced in collisions with simultaneousK-shell ionization is deduced from the measured yield distribution of theK α X-ray satellites. The distribution shows deviations from the binomial ones. The deviations can be accounted for by assuming that theL-shell vacancy production is due to two uncorrelated processes: the direct ionization by impact and the electron capture from theL-shell of the target atom into theK-shell of the projectile, both occurring at nearly central collisions. The corresponding probability values are deduced using simple statistical considerations.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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