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  • Artikel: DFG Deutsche Nationallizenzen  (2)
  • 35A35  (1)
  • Key words Alcohol  (1)
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  • Artikel: DFG Deutsche Nationallizenzen  (2)
Materialart
Erscheinungszeitraum
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Effects of amperozide, 8-OH-DPAT, and FG 5974 on operant responding for ethanol (1998)
    Springer
    Psychopharmacology 137 (1998), S. 25-32 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Key words Alcohol ; Ethanol ; Saccharin ; Self-administration ; Serotonin ; 5-HT1A receptor ; 5-HT2A receptor ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Both 5-HT1A and 5-HT2A receptors have been implicated in modulating ethanol self-administration. A novel serotonergic compound, FG 5974, with combined 5-HT1A agonist/5-HT2A antagonist activities, has shown effects in decreasing ethanol consumption in two-bottle choice paradigms. In the present study, the effect of this compound on operant responding for ethanol (as well as water and a saccharin solution) was compared to compounds possessing the separate neuropharmacological effects of this drug (the 5-HT1A agonist, 8- OH-DPAT, and the 5-HT2A antagonist, amperozide). While all three serotonergic compounds decreased operant responding for ethanol, only FG 5974 had no effect on water and saccharin responding. These results suggest that combined 5HT1A agonist/5-HT2A antagonist activity provides a more selective effect on ethanol reinforcement than either neuropharmacological action alone. Therefore, further analysis of mixed serotonergic compounds in general, and FG 5974 in particular, is warranted as they offer potential treatments for alcoholism.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002130050589
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 2
    Digitale Medien
    Digitale Medien
    The invariant manifold of beam deformations (1993)
    Springer
    Journal of elasticity 30 (1993), S. 1-54 
    Details
    ISSN: 1573-2681
    Schlagwort(e): elastic beam theory ; subcentre invariant manifolds ; dynamical systems ; 73C02 ; 73C10 ; 35A35 ; 58G40
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau , Physik
    Notizen: Abstract The subcentre invariant manifold of elasticity in a thin rod may be used to give a rigorous and appealing approach to deriving one-dimensional beam theories. Here I investigate the analytically simple case of the deformations of a perfectly uniform circular rod. Many, traditionally separate, conventional approximations are derived from within this one approach. Furthermore, I show that beam theories are convergent, at least for the circular rod, and obtain an accurate estimate of the limit of their validity. The approximate evolution equations derived by this invariant manifold approach are complete with appropriate initial conditions, forcing and, in at least one case, boundary conditions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00041769
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
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