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  • Articles: DFG German National Licenses  (5)
  • 4-hydroxy-1,2-dithiolane  (1)
  • Apoptosis  (1)
  • CO3-Apatite  (1)
  • Chemistry  (1)
  • Electron and hole centers  (1)
Source
  • Articles: DFG German National Licenses  (5)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    A new naturally occurring 1,2-dithiolane from Bruguiera cylindrica
    Amsterdam : Elsevier
    Phytochemistry 15 (1976), S. 220-221 
    Details
    ISSN: 0031-9422
    Keywords: 4-hydroxy-1,2-dithiolane ; Bruguiera cylindrica ; Rhizophoraceae ; phenylaminocarbonyl ester.
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)89090-1
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Analysis of paramagnetic centers in X-ray-irradiated enamel, bone, and carbonate-containing hydroxyapatite by electron spin resonance spectroscopy (1979)
    Springer
    Calcified tissue international 28 (1979), S. 107-112 
    Details
    ISSN: 1432-0827
    Keywords: ESR ; Bone ; Enamel ; CO3-Apatite ; Paramagnetism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Carbonate-containing hydroxyapatite, enamel, and bone were irradiated by an X-ray and investigated between 77° and 350°K by means of electron spin resonance (ESR) spectroscopy. The ESR spectrum of enamel irradiated at 77°K in vacuum and observed at the same temperature was almost the same as that of the carbonate-containing hydroxyapatite. The temperature dependence of signal intensities confirms a spin-energy exchange between the mineral and organic constituents in bone, but in enamel no or very little spinenergy exchange between the mineral and organic constituents. Considerable similarity among the ESR spectra of enamel, bone, and carbonate-containing apatite was obtained after X-ray irradiation in air at 300°K with both an X-band and a Q-band ESR spectrometer. The Q-band spectrum can be interpreted in terms of two paramagnetic species. One is identified as a CO 3 3− anion radical which has an axial symmetry withg factors of 2.0029 and 1.9972. The other species is found to be centered atg=2.0019.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441228
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    BCG (bacille Calmette-Guérin)-activated lymphocytes (BAK cells) induce apoptosis in urinary bladder carcinoma cell line T24 in vitro (2000)
    Springer
    International journal of clinical oncology 5 (2000), S. 253-261 
    Details
    ISSN: 1437-7772
    Keywords: Key words BAK cells ; T24 cells ; Apoptosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. We previously reported the basic characteristics of BCG (bacille Calmette-Guérin)-activated killer (BAK) cells, which exhibited antitumor effects against the bladder cancer cell line T24. Our study suggested that both BCG and BAK cells were responsible for the inhibition of tumor cell proliferation; however, the basic mechanism of BCG or BAK cells in this inhibition was not clear. We here report the antitumor effects of BAK cells, which correlated with the induction of apoptosis in T24 cells. Methods. Lymphocytes were cultured with BCG to examine 3H-thymidine uptake, and the subpopulation was evaluated by immunocytometry. T24 cells were then cultured with BAK cells for the analysis of 3H-thymidine uptake and apoptosis induction by DNA electrophoresis; pathology study, and cell-cycle analysis were also done. Culture supernatants of BAK and T24 cells were also investigated to detect interferon-γ (IFN-γ), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α). Results. The 3H-thymidine uptake study of lymphocytes showed that BCG activated the lymphocytes. Evaluation by immunocytometry revealed that CD4+ and CD8+ T cells were induced by BCG. The 3H-thymidine uptake study of T24 cells revealed that BAK cells inhibited tumor cell proliferation. DNA electrophoresis, the morphological study, and cell-cycle analysis by immunocytometry demonstrated that apoptosis in T24 cells was induced when they were cultured with BAK cells. IFN-γ, IL-6, and TNF-α were detected in the culture supernatants of BAK and T24 cells. Conclusions. Cytokine production and the induction of apoptosis may, together, be the major mechanisms of the antitumor action seen when BAK cells were employed against T24 cells; BAK cells could be employed as clinical effectors against bladder cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012046
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Analysis of electron-excess and electron-deficient centers in x-ray-irradiated tricalcium phosphates by electron spin resonance spectroscopy (1979)
    Springer
    Calcified tissue international 29 (1979), S. 239-244 
    Details
    ISSN: 1432-0827
    Keywords: ESR ; Tricalcium phosphates ; Electron and hole centers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary After X-ray irradiation, new paramagnetic centers were observed in electron spin resonance (ESR) spectra of amorphous calcium phosphate (ACP) and Mg-containing tricalcium phosphate (Mg-TCP) when they were heated at 900°C for 1 h before irradiation. Heated ACP shows a single resonance signal atg=2.0005 in place of the hyperfine doublet of the PO 4 2− ion radical, which is the dominant species in the ESR spectrum of unheated ACP. A similar signal is observed in the heated Mg-TCP. Treatment with electron scavengers (Pb2+ and Cd2+) and hole scavengers (Ce3+) suggests that the single resonance signal can be ascribed to a trapped electron. Comparison between the ESR spectra before and after annealing indicates that in the case of the heated ACP such a signal is most likely connected with a localized unpaired electron close to the calcium; on the other hand, in the case of the heated Mg-TCP the signal is connected with the localized electron close to the magnesium. In addition, new sets of signals are observed in those heated samples. Their hyperfine splittings are 612 and 713 gauss for the heated ACP, and 589 and 683 gauss for the heated Mg-TCP. Those new sets of signals are found to be ascribed to the trapped holes close to two magnetically distinct sites of phosphorus nuclei in the crystal lattice ofβ-tricalcium phosphate. Treatment with deuterium oxide strongly indicates that hydrogen atoms originate from adsorbed water molecules, although their half-life is a matter of months even at room temperature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02408086
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Production of L-glutamic acid from hydrocarbons: Incorporation of molecular oxygen (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 9 (1967), S. 45-54 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The production of L-glutamic acid from hydrocarbons by a newly isolated bacterium, which was identified as Corynebacterium, was investigated. The outstanding characteristic of this bacterium was found to be an accessory requirement of thiamine for growth. The optimum concentration of thiamine for growth was 50 μg./liter, while that for L-glutamic acid production was 3-5 μg./liter. n-Paraffins ranging from dodecane to heptadecane were best for L-glutamic acid production, and about 5 g. of L-glutamic acid were obtained from 30 g. of these individual n-paraffins. On the other hand, a tracer experiment using oxygen-18 revealed that molecular oxygen was incorporated into L-glutamic acid produced from dodecane. Based on the incorporation value of molecular oxygen in L-glutamic acid, a hypothetical pathway for the biosynthesis of L-glutamic acid from dodecane was discussed.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260090106
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    Paper (German National Licenses)
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