ISSN:
1432-0878
Schlagwort(e):
Vasomotor nerves
;
Skeletal muscle
;
6-hydroxydopamine
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary Vasomotor nervous distribution to arteries in the cat gastrocnemius and soleus muscles was investigated in the normal and 6-hydroxydopamine treated animal. Muscle samples were processed for the demonstration of acetylcholinesterase by a thiocholine method and for the presence of catecholamines by a formol fluorescence technique. In isolated perfused muscle preparations noradrenaline or adrenaline increased perfusion pressure while acetylcholine or isoprenaline decreased this pressure. A beaded fluorescent periarterial plexus (not visualised after reserpine treatment) was observed. Vasomotor axons, all of which were ACHE-negative, exhibited degenerative changes following 6-hydroxydopamine injection, while ACHE-positive axons outside the adventitial sheath were unaffected. No indication of cholinergic periarterial nerves was found and our evidence suggests that the vasomotor innervation is adrenergic sympathetic in nature.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00935997
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