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  • Articles: DFG German National Licenses  (3)
  • Physics  (2)
  • Acute renal failure  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric nephrology 1 (1987), S. 348-358 
    ISSN: 1432-198X
    Keywords: Acute renal failure ; Glomerular ultrafiltration ; Tubular injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute renal failure (ARF) is a common clinical entity which results from multiple causes. Experimental models in animals have duplicated many of the clinical syndromes which can be classified into (1) ARF due to increased filtered load of endogenous and exogenous materials, (2) ARF associated with exogenous nephrotoxins and (3) ischemic forms of renal failure secondary to hypoperfusion and hypotension. The mechanisms leading to the reduction in GFR are multiple and the alterations in determinants of nephron filtration rate and degree of tubular backleak and obstruction are described for each of these subtypes of experimental ARF. The specific mechanisms whereby tubular damage translates into a reduction in GFR in ARF are discussed for each sub-type of ARF. Tubular damage can often be dissociated from the reduction in GFR, possibly by inhibiting tubuloglomerular feedback responses, but such increases in GFR and nephron filtration rate are not necessarily beneficial to the organism because of potential volume depletion and the risk of magnifying further tubular damage. Information on the physiologic role of tubuloglomerular feedback activity in ARF is provided and supports the concept that feedback induced reductions in GFR after tubular injury may preserve extracellular volume and minimize further tubular damage. Reductions in tubular metabolic work appears to prevent and ameliorate further tubular injury after the initial insult. The mechanisms which associate changes in GFR and tubular damage can now be described, and therapies which improve GFR without correcting the tubular damage may compound the clinical problem and increase renal damage.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 35 (1997), S. 2503-2510 
    ISSN: 0887-6266
    Keywords: rheology ; diffusion ; star-branched polymers ; polyisoprene ; terminal viscosity ; molecular weight dependence ; temperature dependence ; Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Recent experimental investigation of the terminal relaxation in high molecular weight polyisoprenes by dynamic mechanical measurements (C. A. Bero and C.M. Roland, Macromolecules, 29, 1562 (1996)) has found the terminal relaxation times to be more sensitive to changes in temperature for three-arm stars than for the linear polyisoprenes. Moreover, these measurements, carried out with significantly higher molecular weight samples than heretofore, show that the molecular weight dependence of the terminal relaxation times for three-arm star polyisoprenes is much weaker than the exponential dependence previously proposed (L. J. Fetters, et al., Macromolecules, 26, 647 (1993)). Tracer diffusion of labeled linear and three-arm star polyethylene-like diffusant molecules in a highly entangled linear polyethylene matrix exhibit temperature and molecular weight dependencies similar to those observed spectroscopically from bulk polymers. Both the temperature and molecular weight dependencies for the star-branched polymers are at variance with the predictions of the reptation model. It is shown here, however, that these observations can be reconciled through application of the coupling model of relaxation. © 1997 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 35: 2503-2510, 1997
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 22 (1984), S. 79-93 
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: It has been found that flow-induced coalescence occurs at a very rapid rate during the mixing of polymeric fluids. Furthermore, the rheological properties of the dispersed and continuous phases, as well as the nature of the flow field used in their blending, can greatly influence this coalescence. The significance of these findings is that in the development of a mixing scheme to obtain a desired morphology with minimum expenditure of time or energy, attention is usually focused only on the particle breakup aspects of the blending process. The competing coalescence can, however, be accelerated by the same conditions often employed to facilitate particle breakup (e.g., higher shear rates, reduced dispersed-phase viscosity).A better understanding of the mechanism for coalescence of viscoelastic fluids is clearly required. In this manner optimal blending of immiscible polymers can be achieved with respect to both the nature of the final material and the ease with which it is obtained.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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