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  • Articles: DFG German National Licenses  (3)
  • Logistic models  (2)
  • Alanine uptake  (1)
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  • Articles: DFG German National Licenses  (3)
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Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    A predictive model for the treatment approach to community-acquired pneumonia in patients needing ICU admission (1996)
    Springer
    Intensive care medicine 22 (1996), S. 1294-1300 
    Details
    ISSN: 1432-1238
    Keywords: Key words Community-acquired infections ; Bacterial pneumonia ; Intensive Care Units ; Logistic models
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   Objective: To create a predictive model for the treatment approach to community-acquired pneumonia (CAP) in patients needing Intensive Care Unit (ICU) admission. Design: Multicenter prospective study. Setting: Twenty-six Spanish ICUs. Patients: One hundred seven patients with CAP, all of them with accurate etiological diagnosis, divided in three groups according to their etiology in typical (bacterial pneumonia), Legionella and other atypical (Mycoplasma, Chlamydia spp. and virus). For the multivariate analysis we grouped Legionella and other atypical etiologies in the same category. Methods: We recorded 34 variables including clinical characteristics, risk factors and radiographic pattern. We used a multivariate logistic regression analysis to find out a predictive model. Results: We have the complete data in 70 patients. Four variables: APACHE II, (categorized as a dummy variable) serum sodium and phosphorus and “length of symptoms” gave an accurate predictive model (c=0.856). From the model we created a score that predicts typical pneumonia with a sensitivity of 90.2% and specificity 72.4%. Conclusion: Our model is an attempt to help in the treatment approach to CAP in ICU patients based on a predictive model of basic clinical and laboratory information. Further studies, including larger numbers of patients, should validate and investigate the utility of this model in different clinical settings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01709541
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    A predictive model for the treatment approach to community-acquired pneumonia in patients needing ICU admission (1996)
    Springer
    Intensive care medicine 22 (1996), S. 1294-1300 
    Details
    ISSN: 1432-1238
    Keywords: Community-acquired infections ; Bacterial pneumonia ; Intensive Care Units ; Logistic models
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To create a predictive model for the treatment approach to community-acquired pneumonia (CAP) in patients needing Intensive Care Unit (ICU) admission. Design Multicenter prospective study Setting Twenty-six Spanish ICUs. Patients One hundred seven patients with CAP, all of them with accurate etiological diagnosis, divided in three groups according to their etiology in typical (bacterial pneumonia),Legionella and other atypical (Mycoplasma, Chlamydia spp. and virus). For the multivariate analysis we groupedLegionella and other atypical etiologies in the same category. Methods We recorded 34 variables including clinical characteristics, risk factors and radiographic pattern. We used a multivariate logistic regression analysis to find out a predictive model. Results We have the complete data in 70 patients. Four variables: APACHE II, (categorized as a dummy variable) serum sodium and phosphorus and “length of symptoms” gave an accurate predictive model (c=0.856). From the model we created a score that predicts typical pneumonia with a sensitivity of 90.2% and specificity 72.4%. Conclusion Our model is an attempt to help in the treatment approach to CAP in ICU patients based on a predictive model of basic clinical and laboratory information. Further studies, including larger numbers of patients, should validate and investigate the utility of this model in different clinical settings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01709541
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Na+-independent l-alanine uptake by trout cells. Evidence for the existence of at least two functionally different asc systems (1994)
    Springer
    The journal of membrane biology 140 (1994), S. 189-196 
    Details
    ISSN: 1432-1424
    Keywords: Alanine uptake ; Red blood cells ; Peripheral blood lymphocytes ; Isolated hepatocytes ; asc System ; Trout (Salmo trutta)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The Na+-independent uptake of l-alanine has been studied in trout red blood cells, isolated hepatocytes and peripheral blood lymphocytes. The present study shows the existence of two functionally different Na+-independent systems for short chain neutral amino acids in these cells. They are designated as asc systems because of their resemblance to systems described in other cell types. Besides their independence of sodium and a rough similarity in substrate preference, the most important property shared by the two carriers is a lack of trans-stimulation, allowing further differentiation from system L. One of them is an unusually stereospecific carrier present in red blood cells, the other is less restrictive and present in hepatocytes and peripheral blood lymphocytes. Extracellular acid pH increases the incorporation to red blood cells, while it slightly depresses the uptake in the other cells. From the data presented, it is not possible, at first, to classify these carriers as asc 1 or asc 2 systems. Moreover, the system present in red cells resembles that found in the nonerythroid cells, BSC-1, while there is no clear parallelism between the system found in hepatocytes/lymphocytes and any of those described previously.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233707
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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