ISSN:
1438-2199
Keywords:
Amino acids
;
Substance P antagonists
;
Spantide III
;
Solid phase peptide synthesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Five new antagonists of Substance P were designed and synthesized toward increasing potency and safety. One of them was more effective than Spantide II, which was the basis for the design. It was named Spantide III and has the structure: D-NicLys,Pro,Pal,Pro,D-Cl2Phe,Asn,D-Trp,Phe,D-Pal,Leu, NleNH2.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00805985
Permalink