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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 32 (1991), S. 85-86 
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Antiepileptic drugs ; Optimised separation ; Serum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A fast and easy, iscratic high-performance liquid chromatographic method for the simultaneous determination of primidone, phenobarbital, phenytoin, carbamazepine and thiobutabarbital from serum samples has been developed. The optimal eluent composition is 36% acetonitrile, 24% methanol and 40% phosphate buffer. Using a programmable wavelength detector very low (sub-therapeutic) levels of the drugs can be measured.
    Type of Medium: Electronic Resource
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