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  • Articles: DFG German National Licenses  (2)
  • Basal ganglia  (1)
  • Chlamydomonas  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 115 (1997), S. 1-5 
    ISSN: 1432-1106
    Keywords: Key words Procedural learning ; Basal ganglia ; Caudate ; Putamen ; Muscimol ; Monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  To study the role of the basal ganglia in learning of sequential movements, we trained two monkeys to perform a sequential button-press task (2×5 task). This task enabled us to examine the process of learning new sequences as well as the execution of well-learned sequences repeatedly. We injected muscimol (a GABA agonist) into different parts of the striatum to inactivate the local neural activity reversibly. The learning of new sequences became deficient after injections in the anterior caudate and putamen, but not the middle-posterior putamen. The execution of well-learned sequences was disrupted after injections in the middle-posterior putamen and, less severely, after injections in the anterior caudate/putamen. These results suggest that the anterior and posterior portions of the striatum participate in different aspects of learning of sequential movements.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1615-6102
    Keywords: Chlamydomonas ; Pyrenoid ; Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) ; Stroma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The pyrenoid is a protein complex in the chloroplast stroma of eukaryotic algae. After the treatment with mercury chloride, pyrenoids were isolated by sucrose density gradient centrifugation from cell-wall less mutant cells, CW-15, as well as wild type cells, C-9, of unicellular green algaChlamydomonas reinhardtii. Pyrenoids were characterized as a fraction whose protein/chlorophyll ratio was very high, and also examined by Nomarski differential interference microscopy. Most of the components consisted of 55 kDa and 16 kDa polypeptides (1∶1) which were immunologically identified as the large and small subunit of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) protein, respectively. Some minor polypeptides were also detected. Substantial amount of RuBisCO protein is present as a particulate form in the pyrenoid in addition to the soluble form in algal chloroplast stroma.
    Type of Medium: Electronic Resource
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