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  • Articles: DFG German National Licenses  (2)
  • Biosynthesis  (1)
  • Bovine consensus sequence  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Further studies on the biosynthesis of the avermectins (1989)
    Springer
    Journal of industrial microbiology and biotechnology 4 (1989), S. 231-237 
    Details
    ISSN: 1476-5535
    Keywords: Avermectin ; Streptomyces avermitilis ; Biosynthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The biosynthesis of avermectins was studied further inStreptomyces avermitilis MA5502 by feeding experiments with labeled precursors.13C-NMR analysis of the compounds biosynthesized from [2-13C]acetate, [1,2-13C2]acetate, [3-13C]propionate and [2,3-13C2]propionate confirmed that the aglycone of avermectins is made from seven intact acetate and five propionate units. Feeding experiments with [1-13C]2-methylbutyrate and [1-13C]isobutyrate have shown that 2-methylbutyrate and isobutyrate are immediate precursors of the starter units of the polyketide chains of avermectin ‘a’ and ‘b’ components, respectively. The3H/14C doublelabeling experiments suggest that the two oleandrose moieties are derived from glucose.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01574080
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Subfamilies of serine tRNA genes in the bovine genome (1991)
    Springer
    Molecular genetics and genomics 231 (1991), S. 106-112 
    Details
    ISSN: 1617-4623
    Keywords: Serine tDNAs ; Glutamine tDNA ; Bovine consensus sequence ; Short interspersed nuclear element ; Evolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A bovine tRNA gene cluster has been characterized and the sequences of four tDNAs determined. Two of the tDNAs could encode tRNASer IGA, one tDNASer UGA, and the fourth tRNAGln CUG. The three serine tDNAs representing the UCN codon isoacceptor family are almost identical. However, the sequence of the tDNASer TGA differs from a previously sequenced bovine tDNASer TGA at 12 positions (ca. 14%). This finding suggests that in the bovine genome, two subfamilies of genes might encode tRNASer UGA. It also raises the possibility that new genes for a specific UCN isoacceptor might arise from the genes of a different isoacceptor, and could explain previously observed differences between species in the anticodons of coevolving pairs of tRNAsSer UCN. The gene cluster also contains complete and partial copies, and fragments, of the BCS (bovine consensus sequence) SINE (short interspersed nuclear element) family, six examples of which were sequenced. Some of these elements occur in close proximity to two of the serine tDNAs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293828
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    Paper (German National Licenses)
    Fulltext
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