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  • Articles: DFG German National Licenses  (2)
  • Bovine milk immunoglobulins  (1)
  • Cardiac activity  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Treatment of infantile E. coli gastroenteritis with specific bovine anti-E. coli milk immunoglobulins (1979)
    Springer
    European journal of pediatrics 132 (1979), S. 239-252 
    Details
    ISSN: 1432-1076
    Keywords: Bovine milk immunoglobulins ; Treatment of pathogenic E. coli gastroenteritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A milk immunoglobulin concentrate (MIC) containing antibodies to enteropathogenic E. coli strains was prepared by hyperimmunisation of pregnant cows and using the milk obtained during the first 6 to 8 days of lactation. The sterile concentrate contained 70 to 80% protein and 35 to 40% immunoglobulin. The antibacterial activity was measured by bacterial passive agglutination, bacteriostatic activity in vitro, phagocytic clearance in vivo, and a protection test in mice. Though differences in titers were observed, adequate immunologic activity was demonstrated by these tests. Clinical studies were performed with 60 patients (aged 10 days to 18 months) suffering from diarrhoea with isolation of enteropathogenic E. coli. They were treated for 10 days with MIC and stool cultures were done prior to, during, and 2, 3 and 4 days after termination of treatment. Among 51 patients infected with E. coli strains incorporated in the vaccine, stool cultures became negative in 43 (84.3%) after treatment with MIC and 8 remained positive. Nine patients infected with strains O 78: K 80(B-) and O 114: K-(B-)-which were not included in the vaccine used for immunisation—served as controls. Only one patient in this group became negative. If all patients receiving antibiotics for non intestinal infections during the treatment period are omitted the results remained unaltered: MIC was effective in 32 out of 38 patients (84.2%). These differences were highly significant. These results provide evidence that treatment with specific MIC is effective in eliminating enteropathogenic E. coli from the intestine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496847
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of propranolol on whole-body microvibrations during examination stress (1986)
    Springer
    European journal of applied physiology 55 (1986), S. 307-314 
    Details
    ISSN: 1439-6327
    Keywords: Propranolol ; Microvibrations ; Examination stress ; Cardiac activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Whole-body microvibrations (MV) in three dimensions were measured in 51 volunteers, all medical students, 26 without and 25 with beta-receptor blockade (propranolol), immediately before a practical physiology examination and during the ensuing vacation. Propranolol impeded the increase in MV values in all three axes, significantly those in the z axis (vertical), the differences in MV values between the two measurements being minimal in the beta-receptor blocked group. On the other hand, propranolol enhanced MV in the x axis (anteroposterior) and the y axis (transverse), the y axis difference being significant only in females. Propranolol obviously relieves examination stress: the majority of candidates (52%) felt “quieter≓ in the examination with than in other similar situations without beta-receptor blockade. Propranolol was, however, without effect on the examination results. The rectified impulse in the z axis when related to body weight (Jz) correlates linearly with the calculated cardiac output. Propranolol, however, reduced cardiac output more than Jz, pointing to a Jz component non-sensitive to beta-receptor blockade. The part played by muscle tonus, mainly reflected in the y axis, thus remains unknown. The large and slow oscillations in the x and y axes, observed particularly in beta-receptor blocked females, might be attributed to diminution in standing ability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02343804
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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