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  • Articles: DFG German National Licenses  (6)
  • Organic Chemistry  (5)
  • Bovine milk immunoglobulins  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Treatment of infantile E. coli gastroenteritis with specific bovine anti-E. coli milk immunoglobulins (1979)
    Springer
    European journal of pediatrics 132 (1979), S. 239-252 
    Details
    ISSN: 1432-1076
    Keywords: Bovine milk immunoglobulins ; Treatment of pathogenic E. coli gastroenteritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A milk immunoglobulin concentrate (MIC) containing antibodies to enteropathogenic E. coli strains was prepared by hyperimmunisation of pregnant cows and using the milk obtained during the first 6 to 8 days of lactation. The sterile concentrate contained 70 to 80% protein and 35 to 40% immunoglobulin. The antibacterial activity was measured by bacterial passive agglutination, bacteriostatic activity in vitro, phagocytic clearance in vivo, and a protection test in mice. Though differences in titers were observed, adequate immunologic activity was demonstrated by these tests. Clinical studies were performed with 60 patients (aged 10 days to 18 months) suffering from diarrhoea with isolation of enteropathogenic E. coli. They were treated for 10 days with MIC and stool cultures were done prior to, during, and 2, 3 and 4 days after termination of treatment. Among 51 patients infected with E. coli strains incorporated in the vaccine, stool cultures became negative in 43 (84.3%) after treatment with MIC and 8 remained positive. Nine patients infected with strains O 78: K 80(B-) and O 114: K-(B-)-which were not included in the vaccine used for immunisation—served as controls. Only one patient in this group became negative. If all patients receiving antibiotics for non intestinal infections during the treatment period are omitted the results remained unaltered: MIC was effective in 32 out of 38 patients (84.2%). These differences were highly significant. These results provide evidence that treatment with specific MIC is effective in eliminating enteropathogenic E. coli from the intestine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496847
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Tetraphosphorus Decasulfide, Revival of an Old Thionating Agent (1996)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 338 (1996), S. 763-765 
    Details
    ISSN: 0941-1216
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.199633801150
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Über Isoxazolidin-3,5-dione (1965)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 48 (1965), S. 1973-1983 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese von Vertretern der bisher unbekannten Isoxazolidin-3,5-dione durch Umsetzung von Hydroxylamin oder N-monosubstituierten Hydroxylaminen mit substituerten Malonsäurechloriden beschrieben. Eine Anzahl der neuen Verbindungen wirken im Tierexperiment antiphlogistisch.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19650480817
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Ein Beitrag zu den Untersuchungsmethoden der Austauscherkinetik an Ionenaustauschern (1969)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 52 (1969), S. 2137-2143 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Kinetik eines Ionenaustauschprozesses wird mittels einer speziellen polarographischen Untersuchungsmethode untersucht. Die polarisierbare Hg-Elektrode berührt die DONNAN-Flüssigkeit im Zentrum der zylindrischen Ionenaustauschermembran. Das austauschende Ion, zugleich der Depolarisator, diffundiert radial in die Ionenaustauschermembran ein. Durch Vergleich der experimentell erhaltenen Konzentrations-Zeit-Diagramme mit den theoretischen Diagrammen, die sich aus den NERNST-PLANK'schen Beziehungen ergeben, können die Diffusionskoeffizienten des Depolarisators bestimmt werden.Mit dieser Methode wurde die Austauschreaktion von K+ gegen Cd2+ an einem Phenolsulfonsäureharz untersucht, und der Diffusionskoeffizient von Cd2+ im Harz wurde bestimmt.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19690520736
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Zur Herstellung von Benzol-d6 (1958)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 41 (1958), S. 1831-1835 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird ein kontinuierliches Austauschverfahren zur Herstellung grösserer Mengen Benzol-d6 beschrieben. Damit wurde Benzol-d6 mit einem Deuteriumgehalt von 99,3% hergestellt.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19580410638
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Dithio- und Thionester, 56. Zur Reaktion von Thioestern und Thioamiden mit Azodicarbonsäurederivaten (1992)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1992 (1992), S. 927-931 
    Details
    ISSN: 0170-2041
    Keywords: Dithio Esters ; Thiono Esters ; Thioamides ; Azodicarboxylates ; Azodicarboxamides ; Trithiomesoxalamides ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dithio and Thiono Esters, 56.  -  Reaction of Thio Esters and Thio Amides with Azodicarboxylic Acid DerivativesDithio and thiono esters 1 react with azodicarboxylates 3 to form the addition products 4 or the oxidation products 5 in varying ratios. With malonates, malonamides and dithionomalonates only the addition products 7 were obtained. N,N,N′,N′-Tetramethyldithiomalonamide yields with azodicarboxylic acid derivatives 3 either the normal addition product 8, the β-elimination product 9 or N,N,N′,N′-tetramethyltrithiomesoxalamide (10A), the first stable vicinal trithiocarbonyl compound.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.1992199201153
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    Paper (German National Licenses)
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